Bromohydrin reactions of Grieco’s bicyclic lactone

Rodolfo Tello-Aburto; Maria Yolanda Rios; Dale C. Swenson; Horacio F. Olivo

doi:10.1016/j.tetlet.2008.09.081

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Bromohydrin reactions of Grieco’s bicyclic lactone

Journal article

Peer reviewed

Bromohydrin reactions of Grieco’s bicyclic lactone

Rodolfo Tello-Aburto, Maria Yolanda Rios, Dale C. Swenson and Horacio F. Olivo

Tetrahedron letters, Vol.49(48), pp.6853-6855

11/24/2008

DOI: 10.1016/j.tetlet.2008.09.081

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Abstract

The bromohydrin reaction in Grieco’s bicyclic lactone 1 was reinvestigated. Two regioisomeric bromohydrins were obtained ( 2 and 8), and their configurations were unambiguously determined by X-ray diffraction analyses.

Bromohydrin

Grieco’s lactone

Details

Title: Subtitle: Bromohydrin reactions of Grieco’s bicyclic lactone
Creators: Rodolfo Tello-Aburto - Medicinal and Natural Products Chemistry, The University of Iowa, Iowa City, IA 52242, United States
Maria Yolanda Rios - University of Iowa
Dale C. Swenson - University of Iowa
Horacio F. Olivo - University of Iowa
Resource Type: Journal article
Publication Details: Tetrahedron letters, Vol.49(48), pp.6853-6855
Publisher: Elsevier Ltd
DOI: 10.1016/j.tetlet.2008.09.081
ISSN: 0040-4039
eISSN: 1873-3581
Language: English
Date published: 11/24/2008
Academic Unit: Chemistry
Record Identifier: 9984622048002771

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