Journal article
Bronchoscopic imaging of pulmonary mucosal vasculature responses to inflammatory mediators
Journal of Biomedical Optics, Vol.10(3), pp.034013-034015
06/14/2005
DOI: 10.1117/1.1924714
PMID: 16229657
Abstract
In current clinical practice, the initial stage in the detection of pulmonary airway disease is the clinician's interpretation of a bronchoscopy procedure. Due to the nature of this form of detection, diseases are often well advanced upon discovery. This paper proposes a new method for examining the pulmonary airway microcirculatory system via fluorescein imaging techniques similar to those used extensively in ophthalmology. Through the use of a specialized bronchoscopy imaging system we are able to successfully show that fluorescein emission detected in the rabbit trachea exhibits a clear response to inflammatory mediators and thus to changing local vascularity. The clinical implications of this technique are extensive including most importantly the potential use as an evaluation tool for pulmonary disease evaluation and likely other endoscopically accessible organs. ©
Details
- Title: Subtitle
- Bronchoscopic imaging of pulmonary mucosal vasculature responses to inflammatory mediators
- Creators
- Melissa Suter - University of Iowa Hospitals and ClinicsGeoffrey McLennanJoseph Reinhardt - University of IowaPaul R Montague - University of Iowa Hospitals and ClinicsPeter Taft - University of Iowa Hospitals and ClinicsJohn Lee - University of Iowa Hospitals and ClinicsJoseph Zabner - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Journal of Biomedical Optics, Vol.10(3), pp.034013-034015
- DOI
- 10.1117/1.1924714
- PMID
- 16229657
- ISSN
- 1083-3668
- eISSN
- 1560-2281
- Language
- English
- Date published
- 06/14/2005
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Pulmonary, Critical Care, and Occupational Medicine; Public Policy Center (Archive); Internal Medicine
- Record Identifier
- 9984197150902771
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