Journal article
Building and Implementation of a Common Infrastructure for Specimen and Data Storage at an Academic Medical Center
Journal of clinical and translational science, Vol.9(1), pp.1-20
2025
DOI: 10.1017/cts.2025.43
PMCID: PMC12083205
PMID: 40384744
Appears in UI Libraries Support Open Access
Abstract
Precision or “Personalized Medicine” and “Big Data” are growing trends in the biomedical research community and highlight an increased focus on access to larger data sets to effectively explore disease processes at the molecular level versus the previously common one-size-fits all approach. This focus necessitated a local transition from independent lab and siloed projects to a single software application utilizing a common ontology to create access to data from multiple repositories. Use of a common system has allowed for increased ease of collaboration and access to quality biospecimens that are extensively annotated with clinical, molecular, and patient associated data. The software needed to function at an enterprise level while continuing to allow investigators the autonomy and security access they desire. To identify a solution, a
working group comprised of representation from independent repositories and areas of research focus across departments was established and responsible for review and implementation of an enterprise-wide biospecimen management system. Central to this process was the creation of a unified vocabulary across all repositories, including consensus around source of truth, standardized field definitions and shared terminology.
Details
- Title: Subtitle
- Building and Implementation of a Common Infrastructure for Specimen and Data Storage at an Academic Medical Center
- Creators
- Donna A. Santillan - University of IowaLaura Jacobus - University of IowaMichael Henry - University of IowaGeorge J. Weiner - University of IowaPatricia Winokur - University of IowaBoyd M. Knosp - University of IowaHeath A. Davis - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of clinical and translational science, Vol.9(1), pp.1-20
- DOI
- 10.1017/cts.2025.43
- PMID
- 40384744
- PMCID
- PMC12083205
- NLM abbreviation
- J Clin Transl Sci
- ISSN
- 2059-8661
- eISSN
- 2059-8661
- Publisher
- Cambridge University Press; CAMBRIDGE
- Number of pages
- 20
- Grant note
- UI Bioshare service design
The authors would like to thank the members of the University of Iowa community, especially members of the steering committee, who provided helpful discussions and feedback in the UI Bioshare service design. Additionally, we thank the University of Iowa Health Care Information Systems for their technical assistance and support.
- Language
- English
- Electronic publication date
- 03/19/2025
- Date published
- 2025
- Academic Unit
- Molecular Physiology and Biophysics; Infectious Diseases; Hematology, Oncology, and Blood & Marrow Transplantation; Pathology; Pharmaceutical Sciences and Experimental Therapeutics; Radiation Oncology; Obstetrics and Gynecology; Medicine Administration; Internal Medicine
- Record Identifier
- 9984802502702771
Metrics
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