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C3 glomerulopathy: consensus report
Journal article   Open access   Peer reviewed

C3 glomerulopathy: consensus report

Matthew C Pickering, Vivette D D'Agati, Carla M Nester, Richard J Smith, Mark Haas, Gerald B Appel, Charles E Alpers, Ingeborg M Bajema, Camille Bedrosian, Michael Braun, …
Kidney international, Vol.84(6), pp.1079-1089
12/2013
DOI: 10.1038/ki.2013.377
PMCID: PMC3842953
PMID: 24172683
url
https://doi.org/10.1038/ki.2013.377View
Published (Version of record) Open Access

Abstract

C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology, nephrology, complement biology, and complement therapeutics met to discuss C3 glomerulopathy in the first C3 Glomerulopathy Meeting. The objectives were to reach a consensus on: the definition of C3 glomerulopathy, appropriate complement investigations that should be performed in these patients, and how complement therapeutics should be explored in the condition. This meeting report represents the current consensus view of the group.
immunology and pathology complement glomerulonephritis clinical nephrology clinical immunology Meeting Report

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