Journal article
COMIP-001: A clinical 13-antibody, 12-color flow cytometry panel for optimized immunophenotyping of T/NK cells in human leukemia and lymphoma diagnostics
Cytometry. Part B, Clinical cytometry
02/09/2026
DOI: 10.1002/cytob.70015
PMID: 41660867
Abstract
The objective of this 12-color/13-antibody single-tube panel is to assist in the diagnosis of T/NK-cell leukemias and lymphomas. In the clinical setting, the absence of a standardized T/NK-cell panel limits inter-laboratory data comparability, contributes to diagnostic variability, and results in redundant efforts across laboratories to design and validate panels for flow cytometry. Developing and promoting a panel that allows for rapid and fairly comprehensive labeling of surface T/NK-cell markers, including the anti-T-cell receptor beta-chain constant region 1 (TRBC1) antibody, will streamline the workflow by establishing a standard immunophenotyping T/NK-cell panel for detecting neoplastic T/NK cells and lay the foundation for future COMIPs.
Details
- Title: Subtitle
- COMIP-001: A clinical 13-antibody, 12-color flow cytometry panel for optimized immunophenotyping of T/NK cells in human leukemia and lymphoma diagnostics
- Creators
- Nicole So - Tufts UniversitySara Monaghan - University of PittsburghKatelynn Davis - University of PittsburghGrant Bullock - University of IowaWendy Shallenberger - UPMC Health SystemAhmad Al-Attar - University of Pittsburgh
- Resource Type
- Journal article
- Publication Details
- Cytometry. Part B, Clinical cytometry
- DOI
- 10.1002/cytob.70015
- PMID
- 41660867
- NLM abbreviation
- Cytometry B Clin Cytom
- ISSN
- 1552-4949
- eISSN
- 1552-4957
- Publisher
- Wiley
- Number of pages
- 4
- Language
- English
- Electronic publication date
- 02/09/2026
- Academic Unit
- Pathology
- Record Identifier
- 9985139273502771
Metrics
2 Record Views