CORRELATION OF TUMOR-CELL GROWTH IN 4 SEMISOLID SYSTEMS

Z P Pavelic; N J Nowak; H K Slocum; Y M Rustum

doi:10.1007/BF00391838

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CORRELATION OF TUMOR-CELL GROWTH IN 4 SEMISOLID SYSTEMS

Journal article

Open access

Peer reviewed

CORRELATION OF TUMOR-CELL GROWTH IN 4 SEMISOLID SYSTEMS

Z P Pavelic, N J Nowak, H K Slocum and Y M Rustum

Journal of cancer research and clinical oncology, Vol.105(1), pp.94-97

01/01/1983

DOI: 10.1007/BF00391838

PMCID: PMC12252567

PMID: 6339514

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https://www.ncbi.nlm.nih.gov/pmc/articles/12252567View

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Abstract

The correlation of the colony growth of cells disaggregated from human melanoma, sarcoma, lung, and ovarian carcinomas were studied in four different semisolid tissue culture assays: (a) the soft agar assay of Pluznik and Sachs; (b) the soft agar assay of Hamburger and Salmon; (c) the soft agar-methyl cellulose assay of Buick et al.; and (d) the methyl cellulose assay of Ogawa et al. There was no colony growth of tumor cells achieved in 15 of 15 cases assayed in Ogawa's methyl cellulose assay. The plating efficiency of the above mentioned tumors was similar in the assays of Pluznik and Sachs, Hamburger and Salmon, and Buick et al. However, the tumor take rate differed among these three systems. The assay of Buick et al. appears potentially useful for analysis of the biology of human tumors.

Oncology

Life Sciences & Biomedicine

Science & Technology

Details

Title: Subtitle: CORRELATION OF TUMOR-CELL GROWTH IN 4 SEMISOLID SYSTEMS
Creators: Z P Pavelic - Roswell Park Cancer Institute
N J Nowak
H K Slocum - Roswell Park Cancer Institute
Y M Rustum - Roswell Park Cancer Institute
Resource Type: Journal article
Publication Details: Journal of cancer research and clinical oncology, Vol.105(1), pp.94-97
DOI: 10.1007/BF00391838
PMID: 6339514
PMCID: PMC12252567
NLM abbreviation: J Cancer Res Clin Oncol
ISSN: 0171-5216
eISSN: 1432-1335
Publisher: Springer Nature
Number of pages: 4
Grant note: P30CA024538 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) CA-24538; CA-13038; CA-21071 / NCI NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
Language: English
Date published: 01/01/1983
Academic Unit: Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
Record Identifier: 9984360048602771

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