Journal article
COVID-19 Case Fatality and Alzheimer’s Disease
Journal of Alzheimer's disease, Vol.84(4), pp.1447-1452
10/20/2021
DOI: 10.3233/JAD-215161
PMCID: PMC8841099
PMID: 34690147
Abstract
Previous studies have identified dementia as a risk factor for death from coronavirus disease 2019 (COVID-19). However, it is unclear whether Alzheimer’s disease (AD) is an independent risk factor for COVID-19 case fatality rate. In a retrospective cohort study, we identified 387,841 COVID-19 patients through TriNetX. After adjusting for demographics and comorbidities, we found that AD patients had higher odds of dying from COVID-19 compared to patients without AD (Odds Ratio: 1.20, 95%confidence interval: 1.09–1.32, p < 0.001). Interestingly, we did not observe increased mortality from COVID-19 among patients with vascular dementia. These data are relevant to the evolving COVID-19 pandemic.
Details
- Title: Subtitle
- COVID-19 Case Fatality and Alzheimer’s Disease
- Creators
- Qiang Zhang - University of IowaJordan L Schultz - University of IowaGeorgina M Aldridge - University of IowaJacob E Simmering - University of IowaYoungcho Kim - University of IowaAmy C Ogilvie - University of IowaNandakumar S Narayanan - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of Alzheimer's disease, Vol.84(4), pp.1447-1452
- DOI
- 10.3233/JAD-215161
- PMID
- 34690147
- PMCID
- PMC8841099
- ISSN
- 1387-2877
- eISSN
- 1875-8908
- Language
- English
- Date published
- 10/20/2021
- Academic Unit
- Neurology; Pulmonary, Critical Care, and Occupational Medicine; Psychiatry; Health Management and Policy; Epidemiology; Iowa Neuroscience Institute; Pharmacy Practice and Science; Internal Medicine
- Record Identifier
- 9984186940302771
Metrics
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