Journal article
COVID-19 Hospitalization in Adults with Type 1 Diabetes: Results from the T1D Exchange Multicenter Surveillance Study
The journal of clinical endocrinology and metabolism, Vol.106(2), pp.E936-E942
01/23/2021
DOI: 10.1210/clinem/dgaa825
PMCID: PMC7717244
PMID: 33165563
Abstract
Context Diabetes mellitus is associated with increased COVID-19 morbidity and mortality, but there are few data focusing on outcomes in people with type 1 diabetes. Objective The objective of this study was to analyze characteristics of adults with type 1 diabetes for associations with COVID-19 hospitalization. Design An observational multisite cross-sectional study was performed. Diabetes care providers answered a 33-item questionnaire regarding demographics, symptoms, and diabetes- and COVID-19-related care and outcomes. Descriptive statistics were used to describe the study population, and multivariate logistic regression models were used to analyze the relationship between glycated hemoglobin (HbA1c), age, and comorbidities and hospitalization. Setting Cases were submitted from 52 US sites between March and August 2020. Patients or Other Participants Adults over the age of 19 with type 1 diabetes and confirmed COVID-19 infection were included. Interventions None. Main Outcome Measures Hospitalization for COVID-19 infection. Results A total of 113 cases were analyzed. Fifty-eight patients were hospitalized, and 5 patients died. Patients who were hospitalized were more likely to be older, to identify as non-Hispanic Black, to use public insurance, or to have hypertension, and less likely to use continuous glucose monitoring or insulin pumps. Median HbA1c was 8.6% (70 mmol/mol) and was positively associated with hospitalization (odds ratio 1.42, 95% confidence interval 1.18-1.76), which persisted after adjustment for age, sex, race, and obesity. Conclusions Baseline glycemic control and access to care are important modifiable risk factors which need to be addressed to optimize care of people with type 1 diabetes during the worldwide COVID-19 pandemic.
Details
- Title: Subtitle
- COVID-19 Hospitalization in Adults with Type 1 Diabetes: Results from the T1D Exchange Multicenter Surveillance Study
- Creators
- Grenye O'Malley - Icahn School of Medicine at Mount SinaiOsagie Ebekozien - T1D ExchangeMarisa Desimone - SUNY Upstate Medical UniversityCatherina T. Pinnaro - University of IowaAlissa Roberts - University of WashingtonSarit Polsky - University of Colorado Anschutz Medical CampusNudrat Noor - T1D ExchangeGrazia Aleppo - Northwestern UniversityMarina Basina - Stanford UniversityMichael Tansey - University of IowaDevin Steenkamp - Boston Medical CenterFrancesco Vendrame - University of MiamiIlona Lorincz - Hospital of the University of PennsylvaniaPriyanka Mathias - Albert Einstein College of MedicineShivani Agarwal - Albert Einstein College of MedicineLauren Golden - NYU Langone HealthIrl B. Hirsch - University of WashingtonCarol J. Levy - Icahn School of Medicine at Mount Sinai
- Resource Type
- Journal article
- Publication Details
- The journal of clinical endocrinology and metabolism, Vol.106(2), pp.E936-E942
- DOI
- 10.1210/clinem/dgaa825
- PMID
- 33165563
- PMCID
- PMC7717244
- NLM abbreviation
- J Clin Endocrinol Metab
- ISSN
- 0021-972X
- eISSN
- 1945-7197
- Publisher
- Endocrine Soc
- Number of pages
- 7
- Grant note
- Tandem Diabetes Care T1D Exchange Medtronic JDRF; Juvenile Diabetes Research Foundation Dexcom Eli Lilly Abbott Diabetes Helmsley Charitable Trust Insulet Corporation
- Language
- English
- Date published
- 01/23/2021
- Academic Unit
- Endocrinology and Diabetes; Stead Family Department of Pediatrics; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9984353929302771
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