Journal article
COVID-19 Reinfection in Children With Cancer: Clinical Course and Risk Factors
Pediatric blood & cancer, Vol.73(1), e32126
01/2026
DOI: 10.1002/pbc.32126
PMID: 41189086
Abstract
While children with cancer are at risk of severe COVID-19, little is known about reinfection. Among infections (n = 2075) in children (≤ 21 years old, median age = 10 years old) receiving cancer-directed therapy and reported to the Pediatric Oncology COVID-19 case report, reinfection represented 6%. Children with subsequent infections did not have lower odds of hospitalization, intensive care unit admission, or changes to cancer-directed therapy. Odds of reinfection were higher among children with hematologic malignancies but did not vary with sociodemographics, disease status, comorbidities, or vaccination status. The disease course for reinfected children was not less severe than the first infection, emphasizing the importance of preventing reinfection.
Details
- Title: Subtitle
- COVID-19 Reinfection in Children With Cancer: Clinical Course and Risk Factors
- Creators
- Pietro Miozzo - Boston Children's HospitalJoseph-Michael Fields - Massachusetts General HospitalChen Dai - University of Alabama at BirminghamElizabeth S Davis - Boston Medical CenterIsaac Martinez - University of Alabama at BirminghamJulienne Brackett - Texas Children's HospitalDavid S Dickens - University of IowaAlissa R Kahn - St. Joseph’s University Medical CenterCarla Schwalm - Bronson Methodist HospitalArchana Sharma - Rutgers, The State University of New JerseyCatriona Mowbray - Center for Cancer and Blood DisordersJosephine HaDuong - Children's Hospital of Orange CountyJoshua Richman - University of Alabama at BirminghamSmita Bhatia - University of Alabama at BirminghamJennifer M Levine - Center for Cancer and Blood DisordersJulie A Wolfson - University of Alabama at BirminghamEmily E Johnston - University of Alabama at BirminghamPOCC Consortium
- Resource Type
- Journal article
- Publication Details
- Pediatric blood & cancer, Vol.73(1), e32126
- DOI
- 10.1002/pbc.32126
- PMID
- 41189086
- NLM abbreviation
- Pediatr Blood Cancer
- ISSN
- 1545-5017
- eISSN
- 1545-5017
- Publisher
- Wiley
- Grant note
- Concern Foundation
- Language
- English
- Electronic publication date
- 11/04/2025
- Date published
- 01/2026
- Academic Unit
- Stead Family Department of Pediatrics; Hematology/Oncology
- Record Identifier
- 9985024259702771
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