Journal article
COVID-19 Vaccination and Cardiac Arrhythmias: A Review
Current cardiology reports, Vol.29(9), pp.925-940
09/2023
DOI: 10.1007/s11886-023-01921-7
PMID: 37530946
Abstract
Purpose of Review
In this review, we aim to delve into the existing literature, seeking to uncover the mechanisms, investigate the electrocardiographic changes, and examine the treatment methods of various cardiac arrhythmias that occur after administration of the COVID-19 vaccine.
Recent Findings
A global survey has exposed an incidence of arrhythmia in 18.27% of hospitalized COVID-19 patients. Furthermore, any type of COVID-19 vaccine — be it mRNA, adenovirus vector, whole inactivated, or protein subunit — appears to instigate cardiac arrhythmias. Among the cardiac adverse events reported post-COVID-19 vaccination, myocarditis emerges as the most common and is thought to be a potential cause of bradyarrhythmia. When a patient post-COVID-19 vaccination presents a suspicion of cardiac involvement, clinicians should perform a comprehensive history and physical examination, measure electrolyte levels, conduct ECG, and carry out necessary imaging studies.
Summary
In our extensive literature search, we uncovered various potential mechanisms that might lead to cardiac conduction abnormalities and autonomic dysfunction in patients who have received the COVID-19 vaccine. These mechanisms encompass direct viral invasion through molecular mimicry/spike (S) protein production, an escalated inflammatory response, hypoxia, myocardial cell death, and the eventual scar/fibrosis. They correspond to a range of conditions including atrial tachyarrhythmias, bradyarrhythmia, ventricular arrhythmias, sudden cardiac death, and the frequently occurring myocarditis. For treating these COVID-19 vaccination-induced arrhythmias, we should incorporate general treatment strategies, similar to those applied to arrhythmias from other causes.
Details
- Title: Subtitle
- COVID-19 Vaccination and Cardiac Arrhythmias: A Review
- Creators
- Bavithra PariAkhilesh BabbiliAyeesha KattubadiAnuj ThakreSahithreddy ThotamgariRakesh GopinathannairBrian OlshanskyPaari Dominic
- Resource Type
- Journal article
- Publication Details
- Current cardiology reports, Vol.29(9), pp.925-940
- DOI
- 10.1007/s11886-023-01921-7
- PMID
- 37530946
- ISSN
- 1523-3782
- eISSN
- 1534-3170
- Language
- English
- Electronic publication date
- 08/02/2023
- Date published
- 09/2023
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984453201802771
Metrics
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