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CTSA Consortium Consensus Scientific Review Committee (SRC) Working Group Report on the SRC Processes
Journal article   Open access   Peer reviewed

CTSA Consortium Consensus Scientific Review Committee (SRC) Working Group Report on the SRC Processes

Harry P Selker, John B Buse, Robert M Califf, Robert Carter, Dan M Cooper, Jonathan Davis, Daniel E Ford, Pietro Galassetti, Lisa Guay-Woodford, Gordon S Huggins, …
Clinical and translational science, Vol.8(6), pp.623-631
12/2015
DOI: 10.1111/cts.12306
PMCID: PMC4703465
PMID: 26184433
url
https://doi.org/10.1111/cts.12306View
Published (Version of record) Open Access

Abstract

Human research projects must have a scientifically valid study design, analytic plan, and be operationally feasible in order to be successfully completed and thus to have translational impact. To ensure this, institutions that conduct clinical research should have a scientific review process prior to submission to the Institutional Review Committee (IRB). This paper reports the Clinical and Translational Science Award (CTSA) Consortium Scientific Review Committee (SRC) Consensus Working Group's proposed framework for a SRC process. Recommendations are provided for institutional support and roles of CTSAs, multisite research, criteria for selection of protocols that should be reviewed, roles of committee members, application process, and committee process. Additionally, to support the SCR process effectively, and to ensure efficiency, the Working Group recommends information technology infrastructures and evaluation metrics to determine outcomes are provided.
Advisory Committees Awards and Prizes Biomedical Research Consensus Ethics Committees, Research Humans Informed Consent Models, Organizational Program Evaluation Translational Medical Research - trends United States

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