Journal article
Calcifying disorders of the skin
Journal of the American Academy of Dermatology, Vol.33(5), pp.693-706
1995
DOI: 10.1016/0190-9622(95)91803-5
PMID: 7593766
Abstract
Calcium is vital to many biologic processes. In skin, it has a profound effect on keratinocyte proliferation, differentiation, and cell-cell adhesion. Serum calcium is tightly regulated by parathyroid hormone and 1,25(OH)
2D
3. Despite this careful regulation, calcification and ossification of cutaneous and subcutaneous tissues may occur. Cutaneous calcification may be divided into four major categories: dystrophic, metastatic, idiopathic, and iatrogenic. Dystrophic calcification occurs as a results of local tissue injury or abnormalities. Metastatic calcification results from abnormal calcium and/or phosphate metabolism. Virtually any process that calcifies may secondarily ossify. Primary ossification may rarely occur.
Details
- Title: Subtitle
- Calcifying disorders of the skin
- Creators
- John S Walsh - Department of Dermatology, Medical College of Wisconsin, Milwaukee, WisconsinUSAJanet A Fairley - Department of Dermatology, Medical College of Wisconsin, Milwaukee, WisconsinUSA
- Resource Type
- Journal article
- Publication Details
- Journal of the American Academy of Dermatology, Vol.33(5), pp.693-706
- DOI
- 10.1016/0190-9622(95)91803-5
- PMID
- 7593766
- NLM abbreviation
- J Am Acad Dermatol
- ISSN
- 0190-9622
- eISSN
- 1097-6787
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1995
- Academic Unit
- Dermatology
- Record Identifier
- 9984025576202771
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