Journal article
Calcium and the Skin
Archives of dermatology (1960), Vol.124(3), pp.443-444
03/01/1988
DOI: 10.1001/archderm.1988.01670030103034
PMID: 3345095
Abstract
Mother did not know how right she was in exhorting her children to drink milk. In addition to building strong bones and teeth, data have been accumulating that on an "ionic" level calcium regulates cell functions as diverse as insulin secretion, muscle contraction, and mast cell degranulation. In addition, calcium plays an important role in regulating proliferation and differentiation of the skin.Nature maintains steep calcium gradients in and outside cells that allows calcium to act as an internal messenger, translating extracellular signals into cellular responses.1 Calcium is normally stored in the endoplasmic reticulum and mitochondria, and a low, free intracellular concentration in the cytoplasm is maintained (10-7 mol/L). However, the free intracellular calcium is the physiologically active internal calcium. Calcium levels outside the cells and in the storage compartments are 10000 times higher than the free intracellular calcium concentration. Transport of small amounts of calcium from the
Details
- Title: Subtitle
- Calcium and the Skin
- Creators
- Janet A Fairley
- Resource Type
- Journal article
- Publication Details
- Archives of dermatology (1960), Vol.124(3), pp.443-444
- DOI
- 10.1001/archderm.1988.01670030103034
- PMID
- 3345095
- NLM abbreviation
- Arch Dermatol
- ISSN
- 0003-987X
- eISSN
- 1538-3652
- Publisher
- American Medical Association
- Language
- English
- Date published
- 03/01/1988
- Academic Unit
- Dermatology
- Record Identifier
- 9984025557902771
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