Journal article
Cambiarenes: Single‐Step Synthesis and Selective Zwitterion Binding of a Clip‐Shaped Macrocycle with a Redox‐Active Core
Chemistry : a European journal, Vol.26(9), pp.1928-1930
02/11/2020
DOI: 10.1002/chem.201904852
PMID: 31696566
Abstract
A novel macrocyclic host molecule was synthesized that forms in a single step from commercially available starting materials. The core of the macrocycle backbone possesses two quinone rings and, thus, it is redox‐active. Host–guest binding involving the clip‐shaped cavity indicates selective binding of pyridine N‐oxides based on the electron density of and steric bulk around the anionic oxygen.
A novel macrocyclic host molecule has been synthesized that forms in a single step from commercially available starting materials. The core of the macrocycle backbone possesses two quinone rings and, thus, it is redox‐active. Host–guest binding involving the clip‐shaped cavity indicates selective binding of pyridine N‐oxides based on the electron density of and steric bulk around the anionic oxygen.
Details
- Title: Subtitle
- Cambiarenes: Single‐Step Synthesis and Selective Zwitterion Binding of a Clip‐Shaped Macrocycle with a Redox‐Active Core
- Creators
- Riley J Petersen - Central CollegeBrett J Rozeboom - Central CollegeShalisa M Oburn - University of IowaNolan J Blythe - Central CollegeTanner L Rathje - Central CollegeJavier A Luna - University of IowaSteven K Kibby - Central CollegeEmily A O'Brien - Central CollegeKayleigh G Rohr - Central CollegeJoshua R Carpenter - Central CollegeTaylor L Sanders - Central CollegeAndrew M Johnson - Central CollegeKristin M Hutchins - University of IowaScott K Shaw - University of IowaLeonard R MacGillivray - University of IowaJay Wm Wackerly - Central College
- Resource Type
- Journal article
- Publication Details
- Chemistry : a European journal, Vol.26(9), pp.1928-1930
- DOI
- 10.1002/chem.201904852
- PMID
- 31696566
- ISSN
- 0947-6539
- eISSN
- 1521-3765
- Number of pages
- 3
- Grant note
- National Science Foundation (DMR-1408834) American Chemical Society Petroleum Research Fund (#52318-UNI)
- Language
- English
- Date published
- 02/11/2020
- Academic Unit
- Pharmaceutical Sciences and Experimental Therapeutics; Chemistry
- Record Identifier
- 9984216702902771
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