Can dementia be prevented? Brain aging in a population-based context

Mary N Haan; Robert Wallace

doi:10.1146/annurev.publhealth.25.101802.122951

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Can dementia be prevented? Brain aging in a population-based context

Journal article

Open access

Peer reviewed

Can dementia be prevented? Brain aging in a population-based context

Mary N Haan and Robert Wallace

Annual review of public health, Vol.25(1), pp.1-24

2004

DOI: 10.1146/annurev.publhealth.25.101802.122951

PMID: 15015910

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Abstract

As a consequence of global aging of the human population, the occurrence of cognitive impairment and dementia is rapidly becoming a significant burden for medical care and public health systems. By the year 2020, the WHO predicts there will be nearly 29 million demented people in both developed and developing countries. Primary and secondary prevention of dementia through individual and population-level interventions could reduce this imminent risk. Vascular risk factors such as type 2 diabetes, hypertension, dietary fat intake, high cholesterol, and obesity have emerged as important influences on the risk of both vascular and Alzheimer's dementia. Understanding the reasons for differences between populations in genetic vulnerability and environmental exposures may help to identify modifiable risk factors that may lead to effective prevention of vascular and Alzheimer's dementia.

Aged

Aging - physiology

Alzheimer Disease - epidemiology

Alzheimer Disease - genetics

Alzheimer Disease - physiopathology

Alzheimer Disease - prevention & control

Dementia - epidemiology

Dementia - genetics

Dementia - physiopathology

Dementia - prevention & control

Dementia, Vascular - epidemiology

Dementia, Vascular - genetics

Dementia, Vascular - physiopathology

Dementia, Vascular - prevention & control

Environmental Exposure

Health Care Costs

Humans

Incidence

Prevalence

Primary Prevention

Risk Factors

Details

Title: Subtitle: Can dementia be prevented? Brain aging in a population-based context
Creators: Mary N Haan - University of Michigan
Robert Wallace
Resource Type: Journal article
Publication Details: Annual review of public health, Vol.25(1), pp.1-24
DOI: 10.1146/annurev.publhealth.25.101802.122951
PMID: 15015910
NLM abbreviation: Annu Rev Public Health
ISSN: 0163-7525
eISSN: 1545-2093
Grant note: R01 AG012975 / NIA NIH HHS
Language: English
Date published: 2004
Academic Unit: Epidemiology; Injury Prevention Research Center; Internal Medicine
Record Identifier: 9984364444502771

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