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Cancer registry problems in classifying invasive bladder cancer
Journal article   Peer reviewed

Cancer registry problems in classifying invasive bladder cancer

Charles F Lynch, Charles E Platz, Michael P Jones and Jeanne M Gazzaniga
JNCI : Journal of the National Cancer Institute, Vol.83(6), pp.429-433
03/20/1991
DOI: 10.1093/jnci/83.6.429
PMID: 1999849

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Abstract

A slide review of diagnostic pathologic tissue obtained from 364 bladder cancer cases, identified through the Iowa Surveillance, Epidemiology, and End Results (SEER) Program in 1983, classified 97 (26.6%) of these cases as invasive bladder cancers. These findings contrasted sharply with the Iowa SEER Program classification that coded 289 (79.4%) of these cases as invasive bladder cancers. These results were validated further by the hazard ratio of 4.54 (95% confidence interval, 2.57 to 8.03) among invasive relative to noninvasive bladder cancer cases when the slide review findings were used. In contrast, the hazard ratio was only 1.70 (95% confidence interval, 0.76 to 3.79) when the Iowa SEER Program findings were used. The traditional method used by the National Cancer Institute's SEER Program to deal with this problem is described and its implications are discussed.
Registries United States - epidemiology Urinary Bladder Neoplasms - classification Neoplasm Invasiveness - pathology Humans Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - epidemiology Incidence

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