Journal article
Cancer survival among Alaska Native people
Cancer, Vol.124(12), pp.2570-2577
06/15/2018
DOI: 10.1002/cncr.31350
PMCID: PMC6028236
PMID: 29579335
Abstract
BACKGROUND
Recent cancer survival trends among American Indian and Alaska Native (AN) people are not well understood; survival has not been reported among AN people since 2001.
METHODS
This study examined cause‐specific survival among AN cancer patients for lung, colorectal, female breast, prostate, and kidney cancers. It evaluated whether survival differed between cancers diagnosed in 1992‐2002 (the earlier period) and cancers diagnosed in 2003‐2013 (the later period) and by the age at diagnosis (<65 vs ≥65 years), stage at diagnosis (local or regional/distant/unknown), and sex. Kaplan‐Meier and Cox proportional hazards models were used to estimate univariate and multivariate‐adjusted cause‐specific survival for each cancer.
RESULTS
An improvement was observed in 5‐year survival over time from lung cancer (hazard ratio [HR] for the later period vs the earlier period, 0.83; 95% confidence interval [CI], 0.72‐0.97), and a marginally nonsignificant improvement was observed for colorectal cancer (HR, 0.81; 95% CI, 0.66‐1.01). Site‐specific differences in survival were observed by age and stage at diagnosis.
CONCLUSIONS
This study presents the first data on cancer survival among AN people in almost 2 decades. During this time, AN people have experienced improvements in survival from lung and colorectal cancers. The reasons for these improvements may include increased access to care (including screening) as well as improvements in treatment. Improving cancer survival should be a priority for reducing the burden of cancer among AN people and eliminating cancer disparities. Cancer 2018;124:2570‐7. © 2018 American Cancer Society.
This study presents the first data on selected cancer survival among Alaska Native people in almost 2 decades. During this time, Alaska Native people have experienced improvements in survival from lung and colorectal cancers, but survival from breast, prostate, and kidney cancers has not changed.
Details
- Title: Subtitle
- Cancer survival among Alaska Native people
- Creators
- Sarah H Nash - Alaska Native Tribal Health ConsortiumAngela L. W Meisner - University of New Mexico Comprehensive Cancer CenterGarrett L Zimpelman - Alaska Native Tribal Health ConsortiumMarc Barry - University of New MexicoCharles L Wiggins - University of New Mexico
- Resource Type
- Journal article
- Publication Details
- Cancer, Vol.124(12), pp.2570-2577
- DOI
- 10.1002/cncr.31350
- PMID
- 29579335
- PMCID
- PMC6028236
- ISSN
- 0008-543X
- eISSN
- 1097-0142
- Number of pages
- 8
- Grant note
- National Cancer Institute's Surveillance, Epidemiology, and End Results Program (HHSN26120130010I ; HHSN26100005)
- Language
- English
- Date published
- 06/15/2018
- Academic Unit
- Epidemiology; Center for Social Science Innovation
- Record Identifier
- 9984214715802771
Metrics
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