Journal article
Candida auris: The Canary in the Mine of Antifungal Drug Resistance
ACS infectious diseases, Vol.5(9), pp.1487-1492
09/13/2019
DOI: 10.1021/acsinfecdis.9b00239
PMID: 31369237
Abstract
Candia auris has rapidly emerged as a fungal pathogen of worldwide importance. Its impact on global health is due in large part to the high frequency of multidrug resistance among C. auris clinical isolates. Although C. auris resistance to amphotericin B is an unusual feature of this organism, its notoriety should also serve as notice that other more commonly encountered fungal pathogens also show multidrug resistance. Here, we review the epidemiology and mechanisms of C. auris resistance and discuss why the emergence of C. auris provides justification for increased research into mechanisms of drug resistance and the development of novel antifungal drugs.
Details
- Title: Subtitle
- Candida auris: The Canary in the Mine of Antifungal Drug Resistance
- Creators
- Marhiah C Montoya - University of RochesterW. Scott Moye-Rowley - Roy J. and Lucille A. Carver College of MedicineDamian J Krysan - Roy J. and Lucille A. Carver College of Medicine
- Resource Type
- Journal article
- Publication Details
- ACS infectious diseases, Vol.5(9), pp.1487-1492
- DOI
- 10.1021/acsinfecdis.9b00239
- PMID
- 31369237
- NLM abbreviation
- ACS Infect Dis
- ISSN
- 2373-8227
- eISSN
- 2373-8227
- Publisher
- American Chemical Society
- Grant note
- DOI: 10.13039/100000057, name: National Institute of General Medical Sciences, award: GM49825
- Language
- English
- Date published
- 09/13/2019
- Academic Unit
- Molecular Physiology and Biophysics; Microbiology and Immunology; Stead Family Department of Pediatrics; Infectious Disease (Pediatrics); Internal Medicine
- Record Identifier
- 9984297427002771
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