Candidate Gene Analysis: Severe Intraventricular Hemorrhage in Inborn Preterm Neonates

Ulrika Ådén; Aiping Lin; Waldemar Carlo; Alan Leviton; Jeffrey C Murray; Mikko Hallman; Richard P Lifton; Heping Zhang; Laura R Ment

doi:10.1016/j.jpeds.2013.06.025

Back

Candidate Gene Analysis: Severe Intraventricular Hemorrhage in Inborn Preterm Neonates

Journal article

Open access

Peer reviewed

Candidate Gene Analysis: Severe Intraventricular Hemorrhage in Inborn Preterm Neonates

Ulrika Ådén, Aiping Lin, Waldemar Carlo, Alan Leviton, Jeffrey C Murray, Mikko Hallman, Richard P Lifton, Heping Zhang and Laura R Ment

The Journal of pediatrics, Vol.163(5), pp.1503-1506.e1

11/2013

DOI: 10.1016/j.jpeds.2013.06.025

PMCID: PMC3812267

PMID: 23896193

Files and links (1)

url

https://www.ncbi.nlm.nih.gov/pmc/articles/3812267View

Open Access

Abstract

Intraventricular hemorrhage (IVH) is a disorder of complex etiology. We analyzed genotypes for 7 genes from 224 inborn preterm neonates treated with antenatal steroids and grade 3-4 IVH and 389 matched controls. Only methylenetetrahydrofolate reductase was more prevalent in cases of IVH, emphasizing the need for more comprehensive genetic strategies.

COL4A1

MTHFR

IVH

AGA

TNF

Details

Title: Subtitle: Candidate Gene Analysis: Severe Intraventricular Hemorrhage in Inborn Preterm Neonates
Creators: Ulrika Ådén - Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden
Aiping Lin - Department of Pediatrics, Yale University School of Medicine, New Haven, CT
Waldemar Carlo - Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL
Alan Leviton - Department of Neurology, Harvard Medical School, Boston, MA
Jeffrey C Murray - Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA
Mikko Hallman - Deparment of Pediatrics, University of Oulu, Oulu, Finland
Richard P Lifton - Department of Genetics, Yale University School of Medicine, New Haven, CT
Heping Zhang - Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT
Laura R Ment - Department of Pediatrics, Yale University School of Medicine, New Haven, CT
Resource Type: Journal article
Publication Details: The Journal of pediatrics, Vol.163(5), pp.1503-1506.e1
DOI: 10.1016/j.jpeds.2013.06.025
PMID: 23896193
PMCID: PMC3812267
NLM abbreviation: J Pediatr
ISSN: 0022-3476
eISSN: 1097-6833
Publisher: Elsevier Inc
Grant note: NS053865; R01 DA016750-09 / National Institutes of Health
Language: English
Date published: 11/2013
Academic Unit: Anatomy and Cell Biology; Stead Family Department of Pediatrics; Epidemiology; Pediatric Dentistry; Craniofacial Anomalies Research Center; Dental Research
Record Identifier: 9984025302102771

Metrics

31 Record Views

12 Times Cited - Web of Science