Journal article
Captopril Treatment
American journal of diseases of children (1960), Vol.137(9), pp.917-918
09/1983
DOI: 10.1001/archpedi.1983.02140350089026
PMID: 6351596
Abstract
Sir.—In the article "Captopril: Long-term Treatment of Hypertension in a Preterm Infant and in Older Children" (Journal 1983;137:263-266), Hymes and Warshaw reported their experience with captopril (Capoten) in the treatment of hypertensive children and a hypertensive neonate. Only decreased renal function in response to captopril was noted as a complication in their study. However, neutropenia has been reported as an infrequent, dose-related complication of captopril therapy in adults that is secondary to bone marrow suppression.1 We report the occurrence of neutropenia during administration of captopril to a 1,800-g, 15-day-old premature male infant in our nursery who had renovascular hypertension and accumulating plasma captopril concentrations.The patient was born by an uncomplicated vaginal delivery at 34 weeks' gestation after a pregnancy that was complicated by a maternal urinary infection approximately one week before delivery, treated with a sulfonamide antibiotic. Birth weight was 2,150 g. Apgar scores were 9 and
Details
- Title: Subtitle
- Captopril Treatment
- Creators
- DOUGLAS WeismannALLEN ErenbergJEAN RobillardJON Wispe
- Resource Type
- Journal article
- Publication Details
- American journal of diseases of children (1960), Vol.137(9), pp.917-918
- Publisher
- American Medical Association
- DOI
- 10.1001/archpedi.1983.02140350089026
- PMID
- 6351596
- ISSN
- 0002-922X
- eISSN
- 2374-3018
- Number of pages
- 2
- Language
- English
- Date published
- 09/1983
- Academic Unit
- Molecular Physiology and Biophysics; Nephrology, Dialysis and Transplantation; Stead Family Department of Pediatrics; Medicine Administration
- Record Identifier
- 9984773401802771
Metrics
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