Journal article
Captopril renal scintigraphy in renovascular hypertension
American family physician, Vol.55(6), pp.2240-2244
05/01/1997
PMID: 9149651
Abstract
Renovascular disease is a common cause of secondary hypertension. Renal artery stenosis is present in up to one third of patients with clinical markers suggestive of renovascular hypertension, such as hypertension refractory to medical management, severe hypertension in a young patient and worsening of renal function after the use of an angiotensin-converting enzyme inhibitor. Early discovery of renal artery stenosis may allow amelioration or cure of the hypertension and halt progressive loss of renal function. Although renal arteriography remains the gold-standard aid to diagnosis and to planning surgical intervention, it is an invasive procedure that may cause deterioration of renal function. In the presence of renal artery stenosis, glomerular filtration is maintained by angiotensin. Administration of captopril in renal scintigraphy removes this compensatory mechanism and causes a temporary impairment of renal function in the affected kidney. Nuclear tracers can visualize this impairment, thus allowing assessment of the physiologic significance of a renal artery stenosis. The test can be done as a outpatient procedure.
Details
- Title: Subtitle
- Captopril renal scintigraphy in renovascular hypertension
- Creators
- Q T Khairullah - University of Iowa Hospitals and Clinics, Iowa City, USAD L SomersR Aktay
- Resource Type
- Journal article
- Publication Details
- American family physician, Vol.55(6), pp.2240-2244
- PMID
- 9149651
- ISSN
- 0002-838X
- eISSN
- 1532-0650
- Language
- English
- Date published
- 05/01/1997
- Academic Unit
- Nephrology; Internal Medicine
- Record Identifier
- 9984094771502771
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