Journal article
Carbamazepine overdose presenting as a diabetes insipidus like condition in a child
Signa vitae, Vol.10(2), pp.208-215
12/01/2015
DOI: 10.22514/SV102.122015.15
Abstract
Carbamazepine is a commonly used antiepileptic medication. In overdoses it can produce various side effects involving neurological, cardiac, hematological and endocrinal systems. Inappropriate secretion of Anti Diuretic Hormone (ADH) is a well-known complication of carbamazepine toxicity. We are reporting an unusual complication in an adolescent girl with intentional carbamazepine overdose. A sixteen year old female with carbamazepine ingestion presented to our hospital with altered sensorium. On admission she was found to have a very high serum carbamazepine level and metabolic acidosis. In contrast to the possible inappropriate secretion of ADH, as an adverse effect of carbamazepine, her hospital course was complicated with a diabetes insipidus - like condition following treatment with multiple doses of activated charcoal and sodium bicarbonate therapy.
Details
- Title: Subtitle
- Carbamazepine overdose presenting as a diabetes insipidus like condition in a child
- Creators
- Madhuradhar Chegondi - Nemours Children's ClinicAndre RaszynskiBalagangadhar R. Totapally
- Resource Type
- Journal article
- Publication Details
- Signa vitae, Vol.10(2), pp.208-215
- Publisher
- Pharmamed Mado Ltd
- DOI
- 10.22514/SV102.122015.15
- ISSN
- 1334-5605
- eISSN
- 1845-206X
- Number of pages
- 7
- Language
- English
- Date published
- 12/01/2015
- Academic Unit
- Stead Family Department of Pediatrics
- Record Identifier
- 9984354002902771
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