Journal article
Cardiac Metabolism in the Fetus and Newborn
Neoreviews (Elk Grove Village, Ill.), Vol.9(3), pp.e109-e118
03/01/2008
DOI: 10.1542/neo.9-3-e109
Abstract
The heart undergoes marked changes in energy substrate availability, utilization, and metabolic activity during the transition from the fetal to postnatal environment. Availability of these substrates to the newborn is dependent on adequate gas exchange in the lungs, coronary blood flow, and, after a period of time, enteral or parenteral intake of nutrients. At birth, a rapid shift from carbohydrate to fatty acid utilization occurs. However, in the presence of oxygen insufficiency, the neonatal heart retains the capacity to maintain anaerobic energy production and, thus, cardiac function. Despite the importance of adequate cardiac function and the frequency of neonatal hypoxemic conditions, relatively little is known about how the lack of oxygen affects neonatal cardiac function. More studies are required to discern the optimal nutritional management of infants at risk of suffering from myocardial injury related to oxygen deprivation or other alterations of the fetal and postnatal environment.
Details
- Title: Subtitle
- Cardiac Metabolism in the Fetus and Newborn
- Creators
- T. D ScholzJ. L Segar
- Resource Type
- Journal article
- Publication Details
- Neoreviews (Elk Grove Village, Ill.), Vol.9(3), pp.e109-e118
- DOI
- 10.1542/neo.9-3-e109
- ISSN
- 1526-9906
- eISSN
- 1526-9906
- Language
- English
- Date published
- 03/01/2008
- Academic Unit
- Child and Community Health; Fraternal Order of Eagles Diabetes Research Center; Stead Family Department of Pediatrics; Cardiology
- Record Identifier
- 9984093474602771
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