Journal article
Cardiac biomarkers of disordered eating: A case for decreased mean R wave amplitude
Psychiatry research, Vol.272, pp.555-561
02/2019
DOI: 10.1016/j.psychres.2018.12.162
PMID: 30616123
Abstract
•Results of this study show mean R wave amplitude is a promising biomarker to indicate levels of eating disorder symptomatology.•The assessment of mean R wave amplitude in eating disorder populations has important diagnostic, research, and treatment implications.•Mean R wave amplitude is associated with eating disorder symptoms in both clinical and subclinical eating disorder populations.
The purpose of this study was to identify cardiac biomarkers of disordered eating. Mean R wave amplitude (mV), mean T wave amplitude (mV), QRS interval (sec), QTc interval (sec), and Tpeak-Tend interval (sec) were assessed via electrocardiography among women with clinical (n = 53) and subclinical (n = 56) eating disorder symptoms versus asymptomatic controls (n = 32). QRS and QTc intervals were significantly longer and mean T and R wave amplitudes significantly lower among women with clinical symptoms compared to asymptomatic controls. QTc interval length was significantly longer and mean R wave amplitude was significantly lower among women with subclinical symptoms versus asymptomatic controls. Decreased mean R wave amplitude yielded a comparable effect size as QTc when differentiating between asymptomatic and subclinical groups and a larger effect size than QTc when differentiating between asymptomatic and clinical groups, representing a promising clinical biomarker.
Details
- Title: Subtitle
- Cardiac biomarkers of disordered eating: A case for decreased mean R wave amplitude
- Creators
- Melinda Green - Cornell College Eating Disorder Institute, 600 First Street SW, Mt. Vernon, IA 52314, USAAbigail Herrick - Cornell College Eating Disorder Institute, 600 First Street SW, Mt. Vernon, IA 52314, USAEmily Kroska - University of Iowa Department of Psychological and Brain Sciences, W311 Seashore Hall, Iowa City, IA 52242, USAShuhan Reyes - Cornell College Eating Disorder Institute, 600 First Street SW, Mt. Vernon, IA 52314, USAElisabeth Sage - Cornell College Eating Disorder Institute, 600 First Street SW, Mt. Vernon, IA 52314, USALinden Miles - Cornell College Eating Disorder Institute, 600 First Street SW, Mt. Vernon, IA 52314, USA
- Resource Type
- Journal article
- Publication Details
- Psychiatry research, Vol.272, pp.555-561
- Publisher
- Elsevier B.V
- DOI
- 10.1016/j.psychres.2018.12.162
- PMID
- 30616123
- ISSN
- 0165-1781
- eISSN
- 1872-7123
- Language
- English
- Date published
- 02/2019
- Academic Unit
- Psychological and Brain Sciences
- Record Identifier
- 9984214747702771
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