Journal article
Cardiac dysfunction associated with lacosamide in a premature infant with Hypoxic Ischemic Encephalopathy: A case report
American Journal of Perinatology Reports, Vol.14(04), pp.e270-e273
07/2024
DOI: 10.1055/a-2447-8662
PMCID: PMC11597592
PMID: 39600378
Abstract
Lacosamide [Vimpat® Harris FRC Corporation. © 2022 UCB, Inc. Smyrna, GA 30080] is an antiseizure medication which acts through blockage of voltage-gated neuronal sodium channels. Its recent implementation in the neonatal population has been extrapolated from adult and pediatric data suggesting a favorable safety profile. (1) Of note, preterm infants have unique developmental characteristics that may predispose them to increased risk of adverse reactions. We present a case of a preterm neonate who developed left ventricular (LV) dysfunction coinciding with the initiation of lacosamide.
Details
- Title: Subtitle
- Cardiac dysfunction associated with lacosamide in a premature infant with Hypoxic Ischemic Encephalopathy: A case report
- Creators
- Trassanee Chatmethakul - University of Oklahoma Health Sciences CenterAmy Stanford - University of Iowa, Stead Family Department of PediatricsDanielle RiosAdrianne Rahde Bischoff - University of IowaTheresa Czech - University of IowaPatrick McNamara
- Resource Type
- Journal article
- Publication Details
- American Journal of Perinatology Reports, Vol.14(04), pp.e270-e273
- DOI
- 10.1055/a-2447-8662
- PMID
- 39600378
- PMCID
- PMC11597592
- NLM abbreviation
- AJP Rep
- ISSN
- 2157-6998
- eISSN
- 2157-7005
- Publisher
- Thieme Medical Publishers, Inc
- Language
- English
- Electronic publication date
- 09/20/2024
- Date published
- 07/2024
- Academic Unit
- Stead Family Department of Pediatrics; Neurology (Pediatrics); Neonatology; Internal Medicine
- Record Identifier
- 9984738440602771
Metrics
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