Journal article
Cardiovascular morbidity and mortality in bipolar disorder
Annals of clinical psychiatry, Vol.23(1), pp.40-47
02/2011
PMCID: PMC3190964
PMID: 21318195
Abstract
There has been considerable interest in the elevated risk of cardiovascular disease associated with serious mental illness. Although the contemporary literature has paid much attention to major depression and schizophrenia, focus on the risk of cardiovascular mortality for patients with bipolar disorder has been more limited, despite some interest in the historical literature. We reviewed the historical and contemporary literature related to cardiovascular morbidity and mortality in bipolar disorder. In studies that specifically assess cardiovascular mortality, bipolar disorder has been associated with a near doubling of risk when compared with general population estimates. This may be explained by the elevated burden of cardiovascular risk factors found in this population. These findings predate modern treatments for bipolar disorder, which may further influence cardiovascular risk. Given the substantial risk of cardiovascular disease, rigorous assessment of cardiovascular risk is warranted for patients with bipolar disorder. Modifiable risk factors should be treated when identified. Further research is warranted to study mechanisms by which this elevated risk for cardiovascular disease are mediated and to identify systems for effective delivery of integrated medical and psychiatric care for individuals with bipolar disorder.
Details
- Title: Subtitle
- Cardiovascular morbidity and mortality in bipolar disorder
- Creators
- Miriam Weiner - Department of Psychiatry, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242 , USALois WarrenJess G Fiedorowicz
- Resource Type
- Journal article
- Publication Details
- Annals of clinical psychiatry, Vol.23(1), pp.40-47
- Publisher
- United States
- PMID
- 21318195
- PMCID
- PMC3190964
- ISSN
- 1040-1237
- eISSN
- 1547-3325
- Grant note
- UL1 RR024979 / NCRR NIH HHS L30 MH075180 / NIMH NIH HHS 3 UL1 RR024979-03S4 / NCRR NIH HHS 1K23MH083695-01A210 / NIMH NIH HHS K23 MH083695 / NIMH NIH HHS KL2 RR024980 / NCRR NIH HHS
- Language
- English
- Date published
- 02/2011
- Academic Unit
- Psychiatry; Epidemiology; Internal Medicine
- Record Identifier
- 9983931431602771
Metrics
21 Record Views