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Carpal tunnel syndrome in inherited neuropathies: A retrospective survey
Journal article   Peer reviewed

Carpal tunnel syndrome in inherited neuropathies: A retrospective survey

Francis B Panosyan, Callyn A Kirk, Devon Marking, Mary M Reilly, Steven S Scherer, Michael E Shy and David N Herrmann
Muscle & nerve, Vol.57(3), pp.388-394
03/2018
DOI: 10.1002/mus.25742
PMCID: PMC5762426
PMID: 28692128
url
https://www.ncbi.nlm.nih.gov/pmc/articles/5762426View
Open Access

Abstract

ABSTRACT Introduction This study evaluates carpal tunnel syndrome (CTS) symptom severity, functional status, and outcome of CTS therapies in patients with inherited neuropathies. Methods Validated questionnaires were used to compare symptom severity and functional status in patients with and without a diagnosis of CTS and a diagnosis of an inherited neuropathy. Results 309 patients with inherited neuropathies participated in this study. The CTS symptom severity score (SSS) was found to be the most useful tool in assessing CTS severity in patients with inherited neuropathy. Splint therapy and surgery were associated with significant improvement in carpal tunnel symptoms as measured through the SSS. Discussion This study provides insight into the assessment of CTS symptom severity and patient‐reported outcomes to CTS therapy in individuals with inherited neuropathies. The SSS appears useful for evaluation of CTS symptoms and patient‐reported outcomes following CTS interventions in individuals with inherited neuropathies. Muscle Nerve 57: 388–394, 2018
hereditary neuropathy with liability to pressure palsies inherited neuropathy Boston Carpal Tunnel Questionnaire HNPP carpal tunnel syndrome Charcot‐Marie‐Tooth disease CMT

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