Cartilage contact pressure elevations in dysplastic hips: a chronic overload model

Mary E Russell; Kiran H Shivanna; Nicole M Grosland; Douglas R Pedersen

doi:10.1186/1749-799X-1-6

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Cartilage contact pressure elevations in dysplastic hips: a chronic overload model

Journal article

Open access

Peer reviewed

Cartilage contact pressure elevations in dysplastic hips: a chronic overload model

Mary E Russell, Kiran H Shivanna, Nicole M Grosland and Douglas R Pedersen

Journal of orthopaedic surgery and research, Vol.1(1), pp.6-6

2006

DOI: 10.1186/1749-799X-1-6

PMCID: PMC1636031

PMID: 17150126

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https://doi.org/10.1186/1749-799X-1-6View

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Abstract

Background: Developmental dysplasia of the hip (DDH) is a condition in which bone growth irregularities subject articular cartilage to higher mechanical stresses, increase susceptibility to subluxation, and elevate the risk of early osteoarthritis. Study objectives were to calculate three-dimensional cartilage contact stresses and to examine increases of accumulated pressure exposure over a gait cycle that may initiate the osteoarthritic process in the human hip, in the absence of trauma or surgical intervention. Methods: Patient-specific, non-linear, contact finite element models, constructed from computed tomography arthrograms using a custom-built meshing program, were subjected to normal gait cycle loads. Results: Peak contact pressures for dysplastic and asymptomatic hips ranged from 3.56 - 9.88 MPa. Spatially discriminatory cumulative contact pressures ranged from 2.45 - 6.62 MPa per gait cycle. Chronic over-pressure doses, for 2 million cycles per year over 20 years, ranged from 0.463 - 5.85 MPa-years using a 2-MPa damage threshold. Conclusion: There were significant differences between the normal control and the asymptomatic hips, and a trend towards significance between the asymptomatic and symptomatic hips of patients afflicted with developmental dysplasia of the hip. The magnitudes of peak cumulative contact pressure differed between apposed articular surfaces. Bone irregularities caused localized pressure elevations and an upward trend between chronic over-pressure exposure and increasing Severin classification.

Details

Title: Subtitle: Cartilage contact pressure elevations in dysplastic hips: a chronic overload model
Creators: Mary E Russell - Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, USA
Kiran H Shivanna - Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, USA
Nicole M Grosland - Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, Iowa
Douglas R Pedersen - Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, Iowa
Resource Type: Journal article
Publication Details: Journal of orthopaedic surgery and research, Vol.1(1), pp.6-6
DOI: 10.1186/1749-799X-1-6
PMID: 17150126
PMCID: PMC1636031
NLM abbreviation: J Orthop Surg Res
ISSN: 1749-799X
eISSN: 1749-799X
Publisher: BioMed Central; London
Language: English
Date published: 2006
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Orthopedics and Rehabilitation; Injury Prevention Research Center
Record Identifier: 9984040444102771

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