Journal article
Cascade Reactions Using LiAlH4 and Grignard Reagents in the Presence of Water
Angewandte Chemie (International ed.), Vol.47(5), pp.935-939
01/18/2008
DOI: 10.1002/anie.200703002
PMID: 18081114
Abstract
Divided we stand, together we fall: Incompatible reagents, such as water and LiAlH4, Grignard, or cuprate reagents, can be site-isolated on either side of a polydimethylsiloxane (PDMS) thimble (see scheme; SDS=sodium docecyl sulfate) for cascade reactions. The hydrophobic nature of the PDMS membrane prohibits polar molecules, such as water, from diffusing across the membrane.
Details
- Title: Subtitle
- Cascade Reactions Using LiAlH4 and Grignard Reagents in the Presence of Water
- Creators
- M. Brett Runge - University of Iowa, Department of Chemistry, Iowa City, IA 52242, USA, Fax: (+1) 319-335-1270 http://www.chem.uiowa.edu/faculty/bowden/groupMartin T Mwangi - University of Iowa, Department of Chemistry, Iowa City, IA 52242, USA, Fax: (+1) 319-335-1270 http://www.chem.uiowa.edu/faculty/bowden/groupA Lee Miller II - University of Iowa, Department of Chemistry, Iowa City, IA 52242, USA, Fax: (+1) 319-335-1270 http://www.chem.uiowa.edu/faculty/bowden/groupMathew Perring - University of Iowa, Department of Chemistry, Iowa City, IA 52242, USA, Fax: (+1) 319-335-1270 http://www.chem.uiowa.edu/faculty/bowden/groupNed B Bowden - University of Iowa, Department of Chemistry, Iowa City, IA 52242, USA, Fax: (+1) 319-335-1270 http://www.chem.uiowa.edu/faculty/bowden/group
- Resource Type
- Journal article
- Publication Details
- Angewandte Chemie (International ed.), Vol.47(5), pp.935-939
- Publisher
- WILEY-VCH Verlag
- DOI
- 10.1002/anie.200703002
- PMID
- 18081114
- ISSN
- 1433-7851
- eISSN
- 1521-3773
- Number of pages
- 5
- Language
- English
- Date published
- 01/18/2008
- Academic Unit
- Chemistry
- Record Identifier
- 9984216690702771
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