Journal article
Case 38-2007: A 44-Year-Old Woman with Generalized, Painful, Ulcerated Skin Lesions
The New England journal of medicine, Vol.357(24), pp.2496-2505
12/13/2007
DOI: 10.1056/NEJMcpc0706687
PMID: 18077814
Abstract
A 44-year-old woman was admitted to this hospital because of generalized, painful, ulcerated skin lesions. Four years before admission, she had generalized hyperkeratotic lesions that responded poorly to treatment. Biopsy specimens had been interpreted as squamous-cell carcinoma. Three months before admission, mycophenolate mofetil was begun; some of the lesions regressed, but 1 month later, new painful nodules and plaques developed, with central necrosis and ulceration.
A 44-year-old woman was admitted to the hospital because of generalized, painful, ulcerated skin lesions. Three months before admission, mycophenolate mofetil was begun; some of the lesions regressed, but 1 month later, new painful nodules and plaques developed.
Presentation of Case
Dr. Michael Sherling
(Dermatology): A 44-year-old woman was admitted to this hospital because of generalized, painful, ulcerated cutaneous lesions.
The patient had been well, except for eczema, until 4 years before admission, when erosions on the scalp developed, followed by a generalized papular skin eruption. Betamethasone dipropionate and cephalexin were prescribed, without improvement. Examination by a dermatologist 2.3 years before admission revealed scarring alopecia and multiple hyperkeratotic erythematous plaques on the trunk and arms. Pathological examination of biopsy specimens of two lesions on the left arm were reported to show hypertrophic lichenoid dermatitis with eosinophilia. The results . . .
Details
- Title: Subtitle
- Case 38-2007: A 44-Year-Old Woman with Generalized, Painful, Ulcerated Skin Lesions
- Creators
- Vincent LiuCorey S CutlerAlison Z Young
- Resource Type
- Journal article
- Publication Details
- The New England journal of medicine, Vol.357(24), pp.2496-2505
- Publisher
- Massachusetts Medical Society
- DOI
- 10.1056/NEJMcpc0706687
- PMID
- 18077814
- ISSN
- 0028-4793
- eISSN
- 1533-4406
- Language
- English
- Date published
- 12/13/2007
- Academic Unit
- Dermatology; Pathology
- Record Identifier
- 9984025571902771
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