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Case Report: Incidental Finding of COVID-19 Infection after Positron Emission Tomography/CT Imaging in a Patient with a Diagnosis of Histoplasmosis and Recurring Fever
Journal article   Open access   Peer reviewed

Case Report: Incidental Finding of COVID-19 Infection after Positron Emission Tomography/CT Imaging in a Patient with a Diagnosis of Histoplasmosis and Recurring Fever

Camila Edith Stachera Stasiak, David Henrique Nigri, Fabricius Rocha Cardoso, Raphael Santos de Almeida Rezende de Mattos, Philippe Alcantara Goncalves Martins, Alysson Roncally Silva Carvalho, Sergio Altino de Almeida, Rosana Souza Rodrigues and Paulo Henrique Rosado-de-Castro
The American journal of tropical medicine and hygiene, Vol.104(5), pp.1651-1654
04/02/2021
DOI: 10.4269/ajtmh.20-0952
PMCID: PMC8103480
PMID: 33798100
url
https://doi.org/10.4269/ajtmh.20-0952View
Published (Version of record) Open Access

Abstract

This is a case report of a 37-year-old woman evaluated with 18F-fludeoxyglucose (18F-FDG) positron emission computed tomography/CT with recurrent fever after treatment with itraconazole for 6 weeks for histoplas-mosis. The examination demonstrated a decrease in the dimensions of the pulmonary opacities previously identified in the left lower lobe and attributed to histoplasmosis. In addition to these pulmonary opacities, increased FDG uptake was also observed in lymph nodes present in the cervical region, mediastinum, left lung hilum, and hepatic hilum. Notably, other pulmonary opacities with ground-glass pattern that were not present in the previous computed to-mography were detected in the right lower lobe, with mild 18F-FDG uptake. Nasal swab performed shortly after the examination was positive for COVID-19. In this case, the 18F-FDG positron emission computed tomography/CT study demonstrated findings consistent with active COVID-19 infection coexisting with inflammatory changes associated with histoplasmosis infection.
Life Sciences & Biomedicine Public, Environmental & Occupational Health Science & Technology Tropical Medicine

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