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Case Report: Neurobrucellosis Presenting as Malignancy
Journal article   Open access   Peer reviewed

Case Report: Neurobrucellosis Presenting as Malignancy

Andrea S. Salcedo, Xosse Carreras, Takaaki Kobayashi, Jorge L. Salinas, Sara Muñoz, Nelson Diaz and Jorge Alave
The American journal of tropical medicine and hygiene, Vol.111(2), pp.312-316
08/2024
DOI: 10.4269/ajtmh.23-0684
PMCID: PMC11310615
PMID: 38861982
url
https://doi.org/10.4269/ajtmh.23-0684View
Published (Version of record) Open Access

Abstract

Neurobrucellosis, caused by Brucella species, is a zoonotic infection that may involve the central nervous system. Although uncommon, it can manifest as a solitary intracranial mass. We report a case of neurobrucellosis in a 25-year-old woman from Peru who presented with headache, weight loss, and right-side hemiparesis and paresthesia. A contrast-enhanced magnetic resonance imaging scan revealed an intracerebral mass in the left temporal lobe. Serum testing subsequently were positive. Brain biopsy demonstrated non-necrotizing granulomas without malignant cells. Neurobrucellosis should be considered in the differential diagnosis of brain space occupying lesions in endemic countries.

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