Case report: Robotically visualized and biopsy-confirmed peritoneal carcinomatosis as initial identification of metastatic prostate adenocarcinoma in a patient with a history of prostatic urethral lift

Qateeb Khan; Bryn Myers; Breann Bowar; Maryam Khan; Henry Mullaney; Jordan Gainey; Robert Schneider; Laila Dahmoush; Kenneth G. Nepple; James D. Byrne

doi:10.3389/fonc.2023.1284688

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Case report: Robotically visualized and biopsy-confirmed peritoneal carcinomatosis as initial identification of metastatic prostate adenocarcinoma in a patient with a history of prostatic urethral lift

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Case report: Robotically visualized and biopsy-confirmed peritoneal carcinomatosis as initial identification of metastatic prostate adenocarcinoma in a patient with a history of prostatic urethral lift

Qateeb Khan, Bryn Myers, Breann Bowar, Maryam Khan, Henry Mullaney, Jordan Gainey, Robert Schneider, Laila Dahmoush, Kenneth G. Nepple and James D. Byrne

Frontiers in oncology, Vol.13, 1284688

01/19/2024

DOI: 10.3389/fonc.2023.1284688

PMCID: PMC10834618

PMID: 38313211

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Abstract

Background Peritoneal carcinomatosis is a particularly rare presentation of prostate cancer. Here we report a rare clinical case of surgically identified peritoneal carcinomatosis at the time of a planned robotic prostatectomy in a patient with a history of prostatic urethral lift procedure. Case presentation A 72-year-old man, with a history of urinary retention managed with tamsulosin, presented to his local urologist. Prostatic urethral lift procedures were performed for symptom management. After a definitive uptrend in his prostate-specific antigen (PSA) values, a biopsy was obtained, which demonstrated prostate adenocarcinoma. On presurgical multidisciplinary review, it was presumed that he had very high-risk localized prostate cancer. However, upon initiation of robotically assisted laparoscopic radical prostatectomy (RALP), he was noted to have numerous punctate white plaques on the peritoneum; biopsy of these lesions confirmed metastatic disease—for which the patient was starting on triple therapy per the PEACE-1 trial. The PSA level responded appropriately, decreasing from 16.8 to 0.08. Genetic testing was performed and returned negative for any clinically significant mutations. Conclusion Our patient, diagnosed with peritoneal carcinomatosis during a planned RALP, highlights the importance of vigilant laparoscopic exam prior to this prostatectomy. Multidisciplinary discussion is crucial for individualized and optimal treatment planning.

Details

Title: Subtitle: Case report: Robotically visualized and biopsy-confirmed peritoneal carcinomatosis as initial identification of metastatic prostate adenocarcinoma in a patient with a history of prostatic urethral lift
Creators: Qateeb Khan
Bryn Myers
Breann Bowar
Maryam Khan
Henry Mullaney
Jordan Gainey
Robert Schneider
Laila Dahmoush
Kenneth G. Nepple
James D. Byrne
Resource Type: Journal article
Publication Details: Frontiers in oncology, Vol.13, 1284688
DOI: 10.3389/fonc.2023.1284688
PMID: 38313211
PMCID: PMC10834618
NLM abbreviation: Front Oncol
ISSN: 2234-943X
eISSN: 2234-943X
Language: English
Date published: 01/19/2024
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Pathology; Radiation Oncology; Oral and Maxillofacial Surgery; Urology
Record Identifier: 9984548665702771

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