Journal article
Cataract Surgery in Children from Birth to Less than 13 Years of Age: Baseline Characteristics of the Cohort
Ophthalmology (Rochester, Minn.), Vol.123(12), pp.2462-2473
12/2016
DOI: 10.1016/j.ophtha.2016.09.003
PMCID: PMC5121052
PMID: 27769584
Abstract
To describe baseline characteristics, initial postoperative refractive errors, operative complications, and magnitude of the intraocular lens (IOL) prediction error for refractive outcome in children undergoing lensectomy largely in North America. Prospective registry study of children from birth to <13 years of age who underwent lensectomy for any reason within 45 days preceding enrollment. Total of 1266 eyes of 994 children; 49% female and 59% white. Measurement of refractive error, axial length, and complete ophthalmic examination. Eye and systemic associated conditions, IOL style, refractive error, pseudophakic refraction prediction error, operative and perioperative complications. Mean age at first eligible lens surgery was 4.2 years; 337 (34%) were <1 year of age. Unilateral surgery was performed in 584 children (59%). Additional ocular abnormalities were noted in 301 eyes (24%). An IOL was placed in 35 of 460 eyes (8%) when surgery was performed before 1 year of age, in 70 of 90 eyes (78%) from 1 to <2 years of age, and in 645 of 716 eyes (90%) from 2 to <13 years of age. The odds of IOL implantation were greater in children ≥2 years of age than in those <2 years of age (odds ratio = 29.1; P < 0.001; 95% confidence interval: 19.6-43.3). Intraoperative complications were reported for 69 eyes (5%), with the most common being unplanned posterior capsule rupture in 14 eyes, 10 of which had an IOL placed. Prediction error of the implanted IOL was <1.00 diopter in 54% of eyes, but >2.00 diopters in 15% of eyes. Lensectomy surgery was performed throughout childhood, with about two-thirds of cases performed after 1 year of age. Initial surgery seemed safe, with a low complication rate. IOL placement was nearly universal in children 2 years of age and older. The immediate postoperative refraction was within 1 diopter of the target for about one-half of eyes.
Details
- Title: Subtitle
- Cataract Surgery in Children from Birth to Less than 13 Years of Age: Baseline Characteristics of the Cohort
- Creators
- Michael X Repka - Wilmer Institute, Baltimore, Maryland. Electronic address: pedig@jaeb.orgTrevano W Dean - Jaeb Center for Health Research, Tampa, FloridaElizabeth L Lazar - Jaeb Center for Health Research, Tampa, FloridaKimberly G Yen - Baylor College of Medicine/Texas Children's Hospital, Houston, TexasPhoebe D Lenhart - The Emory Eye Center, Atlanta, GeorgiaSharon F Freedman - Duke Eye Center, Durham, North CarolinaDenise Hug - Children's Mercy Hospitals and Clinics, Kansas City, MissouriBahram Rahmani - Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IllinoisSerena X Wang - University of Texas Southwestern, Dallas, TexasRaymond T Kraker - Jaeb Center for Health Research, Tampa, FloridaDavid K Wallace - Duke Eye Center, Durham, North CarolinaPediatric Eye Disease Investigator Group
- Contributors
- Scott A Larson (Contributor) - University of Iowa, Ophthalmology and Visual Sciences
- Resource Type
- Journal article
- Publication Details
- Ophthalmology (Rochester, Minn.), Vol.123(12), pp.2462-2473
- DOI
- 10.1016/j.ophtha.2016.09.003
- PMID
- 27769584
- PMCID
- PMC5121052
- NLM abbreviation
- Ophthalmology
- ISSN
- 0161-6420
- eISSN
- 1549-4713
- Publisher
- United States
- Grant note
- U10 EY018810 / NEI NIH HHS U10 EY023198 / NEI NIH HHS U10 EY011751 / NEI NIH HHS
- Language
- English
- Date published
- 12/2016
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9983980038102771
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