Journal article
Cavum septi pellucidi in normals and patients with schizophrenia as detected by magnetic resonance imaging
Biological psychiatry (1969), Vol.41(11), pp.1102-1108
1997
DOI: 10.1016/S0006-3223(96)00209-0
PMID: 9146821
Abstract
Cavum septi pellucidi (CSP) is a cavity between the two leaflets of the septum pellucidum. CSP is a developmental anomaly, yet the pathologic implications, if any, of an abnormally large CSP remain unclear. The reported incidence of CSP among normal populations varies greatly from 0.15% to 85%. Several studies have suggested that there is a higher incidence of CSP in patients with schizophrenia. We conducted a thin-slice magnetic resonance imaging study to evaluate the prevalence of CSP in a sample of 75 controls and 55 patients. There was a high incidence of small CSP among both groups: 58.8% in the controls and 58.2% in the patients, suggesting that a small cavum could be considered a normal variant; however, the patient group had significantly higher incidence of large CSP (20.7%) compared to the normal group (3%). The patients with large CSP were all male.
Details
- Title: Subtitle
- Cavum septi pellucidi in normals and patients with schizophrenia as detected by magnetic resonance imaging
- Creators
- Peg Nopoulos - The Mental Health Clinical Research Center, University of Iowa Hospital and Clinics, University of Iowa College of Medicine, Iowa City, Iowa, USAVictor Swayze - The Mental Health Clinical Research Center, University of Iowa Hospital and Clinics, University of Iowa College of Medicine, Iowa City, Iowa, USAMichael Flaum - The Mental Health Clinical Research Center, University of Iowa Hospital and Clinics, University of Iowa College of Medicine, Iowa City, Iowa, USAJames C Ehrhardt - Department of Radiology, University of Iowa Hospital and Clinics, University of Iowa College of Medicine, Iowa City, Iowa, USAWilliam T.C Yuh - Department of Radiology, University of Iowa Hospital and Clinics, University of Iowa College of Medicine, Iowa City, Iowa, USANancy C Andreasen - The Mental Health Clinical Research Center, University of Iowa Hospital and Clinics, University of Iowa College of Medicine, Iowa City, Iowa, USA
- Resource Type
- Journal article
- Publication Details
- Biological psychiatry (1969), Vol.41(11), pp.1102-1108
- Publisher
- Elsevier Inc
- DOI
- 10.1016/S0006-3223(96)00209-0
- PMID
- 9146821
- ISSN
- 0006-3223
- eISSN
- 1873-2402
- Language
- English
- Date published
- 1997
- Academic Unit
- Neurology; Radiology; Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984003931402771
Metrics
30 Record Views