Journal article
Center-specific variation in outcomes for extremely premature, extremely low birth weight neonates
Frontiers in pediatrics, Vol.13, 1570542
06/01/2025
DOI: 10.3389/fped.2025.1570542
PMCID: PMC12226493
PMID: 40620853
Abstract
The survival rate of neonates born with extremely low birth weight (<1,000 g) and extremely preterm (<29 gestational age) has significantly improved with advances in neonatal care. Despite such advances, outcomes vary widely across neonatal intensive care units due to differences in care practices and patient population. In this study, we examined 1,627 extremely low birth weight and extremely preterm infants admitted to three NICUs across the United States between 2013 and 2023. We evaluated survival and severe intraventricular hemorrhage (SIVH) using statistical models that were adjusted for maternal and neonatal characteristics. Significant differences in outcomes were observed between the centers. These differences were associated with variations in care practices, including resuscitation decisions for the infants. Despite these differences, all centers achieved survival without SIVH for a substantial number of infants, annually. These findings emphasize the need for evidence-based practice-sharing and improvements to ensure better and more consistent care.
Details
- Title: Subtitle
- Center-specific variation in outcomes for extremely premature, extremely low birth weight neonates
- Creators
- Sai Manasa Kalyanam - Johns Hopkins UniversityJordan R. Kuiper - George Washington UniversityTheodore J. Iwashyna - Johns Hopkins UniversityLindsey A. Knake - University of IowaEsther G. Lee - Rush UniversityJames L. Wynn - University of Florida HealthKhyzer B. Aziz - Johns Hopkins University
- Resource Type
- Journal article
- Publication Details
- Frontiers in pediatrics, Vol.13, 1570542
- DOI
- 10.3389/fped.2025.1570542
- PMID
- 40620853
- PMCID
- PMC12226493
- NLM abbreviation
- Front Pediatr
- ISSN
- 2296-2360
- eISSN
- 2296-2360
- Publisher
- Frontiers Media S.A
- Language
- English
- Date published
- 06/01/2025
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984833489802771
Metrics
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