Journal article
Central Nervous System Infections Due to Streptococcus anginosus Group: A Single-Center Case Series
Journal of child neurology, Vol.37(3), pp.210-217
12/01/2021
DOI: 10.1177/08830738211052132
Abstract
Background The Streptococcus anginosus group is known for its pathogenicity and tendency for abscess formation. The S anginosus group also causes brain abscesses, yet few studies describe this presentation in the pediatric neurology literature. We describe 5 patients with central nervous system infection due to S anginosus group evaluated by child neurologists at the University of Iowa from 2014 to 2020. Methods We performed a retrospective case series review of electronic medical records detailing the clinical presentation and course of pediatric patients with S anginosus group–associated central nervous system infection. Results We identified 4 males and 1 female (8, 11, 14, 16, and 21 years). Brain imaging showed abscesses in 4 cases and empyema in 1. All underwent neurosurgical intervention and antibiotic treatment. Cultures obtained during the neurosurgical procedure grew S anginosus group (4 cases with Streptococcus intermedius and 1 with Streptococcus constellatus). An 8-year-old boy with a delayed diagnosis died from brain herniation. Conclusions Central nervous system infections due to the S anginosus group can be life-threatening. Neuroimaging plays a key role in the early identification of abscesses. Prompt surgical intervention and timely initiation of antibiotics are critical for optimal outcomes.
Details
- Title: Subtitle
- Central Nervous System Infections Due to Streptococcus anginosus Group: A Single-Center Case Series
- Creators
- Sujana Madathil - University of IowaSatsuki Matsumoto - University of IowaKatherine D Mathews - University of IowaJoseph Glykys - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of child neurology, Vol.37(3), pp.210-217
- DOI
- 10.1177/08830738211052132
- ISSN
- 0883-0738
- eISSN
- 1708-8283
- Language
- English
- Date published
- 12/01/2021
- Academic Unit
- Neurology; Iowa Neuroscience Institute; Stead Family Department of Pediatrics; Neurology (Pediatrics)
- Record Identifier
- 9984199817102771
Metrics
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