Journal article
Central nervous system complications after allogeneic hematopoietic stem cell transplantation
Future oncology (London, England), Vol.13(25), pp.2297-2312
10/01/2017
DOI: 10.2217/fon-2017-0274
PMID: 28984145
Abstract
Allogenic hematopoietic stem cell transplant (alloSCT) is a potentially curative modality of treatment for patients with hematological malignancies. However, CNS complications following transplant pose a risk to survival of the patients. Early recognition and management of these complications are crucial to reduce morbidity and mortality of patients following transplant. Early CNS complications associated with alloSCT are infection, cerebrovascular events, chemotherapy and radiation-induced toxicities while late complications include post-transplant lymphoproliferative disorder, CNS relapse of underlying malignancy and viral and fungal infections. Development of graft-versus-host disease can further increase the risk of CNS complications and outcomes after alloSCT. Strategies aimed to reduce the risk of CNS complications
Details
- Title: Subtitle
- Central nervous system complications after allogeneic hematopoietic stem cell transplantation
- Creators
- Ranjit Kumar Chaudhary - Tribhuvan UniversityPrajwal Dhakal - Michigan State UniversityAashrayata Aryal - University of Nebraska Medical CenterVijaya Raj Bhatt - University of Nebraska Medical Center
- Resource Type
- Journal article
- Publication Details
- Future oncology (London, England), Vol.13(25), pp.2297-2312
- Publisher
- Future Medicine Ltd
- DOI
- 10.2217/fon-2017-0274
- PMID
- 28984145
- ISSN
- 1479-6694
- eISSN
- 1744-8301
- Number of pages
- 16
- Language
- English
- Date published
- 10/01/2017
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9984360148102771
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