Journal article
Cerebellar hypoactivity in frequent marijuana users
Neuroreport, Vol.11(4), pp.749-753
03/20/2000
DOI: 10.1097/00001756-200003200-00019
PMID: 10757513
Abstract
It is uncertain whether frequent marijuana use adversely affects human brain function. Using PET, regional cerebral blood flow was compared in frequent marijuana users and comparable, non-using controls after at least 26 h of monitored abstention by all subjects. Marijuana users showed substantially lower brain blood flow than controls in a large region of posterior cerebellum, indicating altered brain function in frequent marijuana users. A cerebellar locus of some chronic and acute effects of marijuana is plausible, e.g. the cerebellum has been linked to an internal timing system, and alterations of time sense are common following marijuana smoking.
Details
- Title: Subtitle
- Cerebellar hypoactivity in frequent marijuana users
- Creators
- Robert Block - 1Department of Anesthesia, Westlawn Building, Room 5140, Iowa City, IA 52242 USA 2Department of Psychiatry, University of Iowa, Iowa City, IA 52242 USA 3Department of Radiology, University of Iowa, Iowa City, IA 52242 USA 4Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242 USA 5Department of Speech Pathology and Audiology, University of Iowa, Iowa City, IA 52242 USA 6Department of Psychology, University of Iowa, Iowa City, IA 52242 USA 7School of Social Work, University of Iowa, Iowa City, IA 52242 USA 8Present address: Alzheimerʼs Research Unit, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA 02129, USADaniel OʼLearyRichard HichwaJean AugustinackLaura PontoM GhoneimStephan ArndtJames EhrhardtRichard HurtigG WatkinsJames HallPeter NathanNancy Andreasen
- Resource Type
- Journal article
- Publication Details
- Neuroreport, Vol.11(4), pp.749-753
- DOI
- 10.1097/00001756-200003200-00019
- PMID
- 10757513
- NLM abbreviation
- Neuroreport
- ISSN
- 0959-4965
- eISSN
- 1473-558X
- Publisher
- Lippincott Williams & Wilkins, Inc
- Language
- English
- Date published
- 03/20/2000
- Academic Unit
- Radiology; Communication Sciences and Disorders; Psychiatry; Research Administration; Iowa Neuroscience Institute; Pharmaceutical Sciences and Experimental Therapeutics; Biostatistics; Physics and Astronomy; Radiation Oncology; Nursing; Anesthesia; Injury Prevention Research Center
- Record Identifier
- 9984003458902771
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