Journal article
Cerebral blood flow and neuropsychological functioning in elderly vascular disease patients
Journal of clinical and experimental neuropsychology, Vol.34(2), pp.220-225
02/01/2012
DOI: 10.1080/13803395.2011.630653
PMCID: PMC3582376
PMID: 22149630
Abstract
This study was designed to determine the relationships between positron emission tomography (PET)-based quantitative measures of cerebral blood flow and cerebrovascular reserve and neuropsychological functioning in elderly individuals with atherosclerotic vascular disease. It was hypothesized that cerebrovascular function would be significantly associated with neuropsychological functioning. Results showed that both baseline global cerebral blood flow and cerebrovascular reserve were significantly associated with global neuropsychological functioning, when controlling for age and sex. Cerebrovascular reserve was additionally associated with performance on measures of memory and attention. Additional research is needed to determine whether measures of cerebral blood flow can be used to predict cognitive decline.
Details
- Title: Subtitle
- Cerebral blood flow and neuropsychological functioning in elderly vascular disease patients
- Creators
- David J Moser - Department of Psychiatry , University of Iowa Carver College of MedicineLaura L Boles Ponto - Division of Nuclear Medicine, Department of Radiology , University of Iowa Carver College of MedicineIvy N Miller - Department of Psychology , Boston UniversitySusan K Schultz - Department of Psychiatry , University of Iowa Carver College of MedicineYusuf Menda - Division of Nuclear Medicine, Department of Radiology , University of Iowa Carver College of MedicineStephan Arndt - Department of Psychiatry , University of Iowa Carver College of MedicinePeggy C Nopoulos - Department of Psychiatry , University of Iowa Carver College of Medicine
- Resource Type
- Journal article
- Publication Details
- Journal of clinical and experimental neuropsychology, Vol.34(2), pp.220-225
- DOI
- 10.1080/13803395.2011.630653
- PMID
- 22149630
- PMCID
- PMC3582376
- NLM abbreviation
- J Clin Exp Neuropsychol
- ISSN
- 1380-3395
- eISSN
- 1744-411X
- Publisher
- Taylor & Francis Group
- Language
- English
- Date published
- 02/01/2012
- Academic Unit
- Neurology; Radiology; Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Pharmaceutical Sciences and Experimental Therapeutics; Biostatistics; Radiation Oncology; Nursing; Injury Prevention Research Center; Medicine Administration; Internal Medicine
- Record Identifier
- 9984003919502771
Metrics
25 Record Views