Changes in physical and mental health are associated with cardiovascular disease incidence in postmenopausal women

Nazmus Saquib; Robert Brunner; Manisha Desai; Candyce Kroenke; Lisa W Martin; Martha Daviglus; Norrina B Allen; Jennifer Robinson; Hilary Tindle; Marcia L Stefanick

doi:10.1093/ageing/afy213

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Changes in physical and mental health are associated with cardiovascular disease incidence in postmenopausal women

Journal article

Open access

Peer reviewed

Changes in physical and mental health are associated with cardiovascular disease incidence in postmenopausal women

Nazmus Saquib, Robert Brunner, Manisha Desai, Candyce Kroenke, Lisa W Martin, Martha Daviglus, Norrina B Allen, Jennifer Robinson, Hilary Tindle and Marcia L Stefanick

Age and ageing, Vol.48(3), pp.448-453

05/01/2019

DOI: 10.1093/ageing/afy213

PMID: 30753250

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Abstract

physical and mental health are important risk factors for cardiovascular disease (CVD) incidence and death among postmenopausal women. The objective of this study was to assess whether changes in physical and mental health were associated with CVD incidence and death. in the Women's Health Initiative Observational Study, 48,906 women (50-79 years) had complete data at baseline on physical and mental health (assessed with Short Form-36) and key covariates. Changes in self-reported physical and mental health were calculated between baseline and year 3. Incident CVD and death between year 3 and end of the study were verified with medical records. over a median 8.2-year follow-up, 2,319 women developed CVD, and 1,571 women died, including 361 CVD deaths. Women with continued poor health and those with worsened health had significantly increased risk of CVD incidence, CVD-specific death and all-cause death relative to women with continued good health. Both major and minor declines in physical health were associated with an increased risk of these outcomes relative to women with no change in physical health. Only major declines in mental health were associated with poor prognosis. changes in physical and mental health over 3 years were independently associated with subsequent CVD events.

Cardiovascular Diseases - etiology

Humans

Middle Aged

Risk Factors

Postmenopause - psychology

Mental Health

Incidence

Cardiovascular Diseases - epidemiology

Cardiovascular Diseases - mortality

Female

Surveys and Questionnaires

Aged

Health Status

Postmenopause - physiology

Details

Title: Subtitle: Changes in physical and mental health are associated with cardiovascular disease incidence in postmenopausal women
Creators: Nazmus Saquib - College of Medicine, Sulaiman Al-Rajhi Colleges, Al-Qassim, Saudi Arabia
Robert Brunner - University of Nevada, Reno, USA
Manisha Desai - Department of Medicine, School of Medicine, Stanford University, Stanford, USA
Candyce Kroenke - Kaiser Permanente, Oakland, USA
Lisa W Martin - George Washington University, Washington, USA
Martha Daviglus - Northwestern University, Chicago, USA
Norrina B Allen - Northwestern University, Chicago, USA
Jennifer Robinson - The University of Iowa, Iowa City, USA
Hilary Tindle - University of Pittsburgh, Pittsburgh, USA
Marcia L Stefanick - Department of Medicine, School of Medicine, Stanford University, Stanford, USA
Resource Type: Journal article
Publication Details: Age and ageing, Vol.48(3), pp.448-453
DOI: 10.1093/ageing/afy213
PMID: 30753250
NLM abbreviation: Age Ageing
ISSN: 0002-0729
eISSN: 1468-2834
Publisher: England
Grant note: DOI: 10.13039/100000002, name: NIH
Language: English
Date published: 05/01/2019
Academic Unit: Epidemiology; Fraternal Order of Eagles Diabetes Research Center; Internal Medicine
Record Identifier: 9983996065502771

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7 Times Cited - Web of Science