Journal article
Changes over time in endorsement of 11 DSM-IV alcohol use disorder (AUD) criteria in young adults with persistent or recurrent AUD in the Collaborative Study on the Genetics of Alcoholism
Alcoholism, clinical and experimental research, Vol.47(5), pp.919-929
05/2023
DOI: 10.1111/acer.15054
PMCID: PMC10308878
PMID: 36924463
Abstract
Endorsement of specific DSM-IV alcohol use disorder (AUD) criteria items changed significantly over time in men in their thirties with persistent or recurrent AUD. Few studies have documented whether endorsement of AUD items change over time in younger individuals or in women. The prospective analyses presented here evaluate changes in endorsement of AUD criteria in 377 men and women with persistent or recurrent AUD during their twenties.
AUD item endorsement over time between average ages of 20 and 25 in 223 men and 154 women with persistent or recurrent AUD in at least three interviews were available from participants in the Collaborative Study on the Genetics of Alcoholism. Statistical significance of endorsement changes over time were evaluated using related-samples Cochran's Q for the full sample and for men and women separately. Additional analyses evaluated potential sex differences in the patterns of change.
In the full sample, the predominant pattern was for significant increased rates of endorsements for six of the seven alcohol dependence criteria, but not in the four abuse items. A similar pattern was seen within men, but women demonstrated significant changes in only three of the seven dependence criteria.
Endorsement of the seven alcohol dependence criteria during the twenties generally increased in individuals with persistent or recurrent AUD, but few changes were observed regarding rates of endorsement of the four abuse items. The paper discusses how the results might reflect on the nature of AUD and on the DSM criteria.
Details
- Title: Subtitle
- Changes over time in endorsement of 11 DSM-IV alcohol use disorder (AUD) criteria in young adults with persistent or recurrent AUD in the Collaborative Study on the Genetics of Alcoholism
- Creators
- Marc A Schuckit - University of California San DiegoTom L Smith - University of California San DiegoGeorge Danko - University of California San DiegoJake Tear - University of California San DiegoJessica Hennies - University of California San DiegoLee Anne Mendoza - University of California San DiegoVictor Hesselbrock - University of ConnecticutHoward J Edenberg - Indiana UniversityMichie Hesselbrock - University of ConnecticutKathleen Bucholz - Washington Univ. School of Medicine, Psychiatry 4560 Clayton Ave Suite 1000, Saint Louis, MO, USA, 6311Grace Chan - UConn HealthSamuel Kuperman - University of IowaMeredith W FrancisMartin H Plawecki - Indiana University
- Resource Type
- Journal article
- Publication Details
- Alcoholism, clinical and experimental research, Vol.47(5), pp.919-929
- DOI
- 10.1111/acer.15054
- PMID
- 36924463
- PMCID
- PMC10308878
- NLM abbreviation
- Alcohol Clin Exp Res
- ISSN
- 0145-6008
- eISSN
- 1530-0277
- Language
- English
- Electronic publication date
- 03/16/2023
- Date published
- 05/2023
- Academic Unit
- Psychiatry
- Record Identifier
- 9984378110202771
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