Journal article
Changing antipsychotic medication: guidelines on the transition to treatment with Risperidone
Clinical therapeutics, Vol.18(4), pp.592-607
1996
DOI: 10.1016/S0149-2918(96)80211-6
PMID: 8879889
Abstract
When treating patients with psychoses, clinicians must often consider changing their treatment from one antipsychotic agent to another. The transition may be necessary because the patient experiences serious side effects or because the existing therapy no longer controls the patient's symptoms. A principal problem in changing antipsychotic agents is the potential for withdrawal symptoms resulting from discontinuation of the existing therapy. These syndromes can manifest as reemergence or worsening of psychosis, rebound or unmasked dyskinesia, and cholinergic-rebound symptoms. Withdrawal signs and symptoms may include insomnia, nausea, vomiting, anxiety, and agitation. When switching a patient to the new antipsychotic agent risperidone, the clinician can keep withdrawal symptoms to a minimum by considering the patient's clinical history and current status. For some patients, abrupt withdrawal of the current antipsychotic may be possible. For others, the dose of the previous medication must be gradually reduced before risperidone is initiated. In many cases, the transition is best made by overlapping the existing therapy and risperidone.
Details
- Title: Subtitle
- Changing antipsychotic medication: guidelines on the transition to treatment with Risperidone
- Creators
- Richard L Borison - Medical College of Georgia, School of Medicine, Augusta, Georgia U.S.AConsensus Study Group on Risperidone Dosing
- Contributors
- Del D Miller (Contributor) - University of Iowa, Psychiatry
- Resource Type
- Journal article
- Publication Details
- Clinical therapeutics, Vol.18(4), pp.592-607
- DOI
- 10.1016/S0149-2918(96)80211-6
- PMID
- 8879889
- NLM abbreviation
- Clin Ther
- ISSN
- 0149-2918
- eISSN
- 1879-114X
- Publisher
- EM Inc USA
- Language
- English
- Date published
- 1996
- Academic Unit
- Psychiatry
- Record Identifier
- 9984003457702771
Metrics
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