Journal article
Channel noise in neurons
Trends in Neurosciences, Vol.23(3), pp.131-137
2000
DOI: 10.1016/S0166-2236(99)01521-0
PMID: 10675918
Abstract
The probabilistic gating of voltage-dependent ion channels is a source of electrical ‘channel noise’ in neurons. This noise has long been implicated in limiting the reliability (repeatability) of neuronal responses to repeated presentations of identical stimuli. More recently, it has been shown to increase the range of spiking behaviors exhibited in some neural populations. Channel numbers are tied to metabolic efficiency and the stability of resting potential, and channel noise might be exploited by future cochlear implants in order to improve the temporal representation of sound.
Details
- Title: Subtitle
- Channel noise in neurons
- Creators
- John A White - Dept of Biomedical Engineering and Center for BioDynamics, Boston University, Boston, MA 02215, USAJay T Rubinstein - Depts of Otolaryngology-Head and Neck Surgery, and Physiology and Biophysics, University of Iowa College of Medicine, Iowa City, IA 52242, USAAlan R Kay - Alan R. Kay is at the Dept of Biological Sciences, University of Iowa, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- Trends in Neurosciences, Vol.23(3), pp.131-137
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/S0166-2236(99)01521-0
- PMID
- 10675918
- ISSN
- 0166-2236
- eISSN
- 1878-108X
- Language
- English
- Date published
- 2000
- Academic Unit
- Iowa Neuroscience Institute; Biology
- Record Identifier
- 9983991956902771
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