Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence Summary

Sajjad Shirazi; Clark M. Stanford; Lyndon F. Cooper

doi:10.3390/jcm10061158

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Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence Summary

Journal article

Open access

Peer reviewed

Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence Summary

Sajjad Shirazi, Clark M. Stanford and Lyndon F. Cooper

Journal of clinical medicine, Vol.10(6), pp.1-12

03/01/2021

DOI: 10.3390/jcm10061158

PMCID: PMC8000787

PMID: 33802043

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Abstract

Knowledge about the detection potential and detection rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in various body fluids and sites is important for dentists since they, directly or indirectly, deal with many of these fluids/sites in their daily practices. In this study, we attempt to review the latest evidence and meta-analysis studies regarding the detection rate of SARS-CoV-2 in different body specimens and sites as well as the characteristics of these sample. The presence/detection of SARS-CoV-2 viral biomolecules (nucleic acid, antigens, antibody) in different clinical specimens depends greatly on the specimen type and timing of collection. These specimens/sites include nasopharynx, oropharynx, nose, saliva, sputum, bronchoalveolar lavage, stool, urine, ocular fluid, serum, plasma and whole blood. The relative detection rate of SARS-CoV-2 viral biomolecules in each of these specimens/sites is reviewed in detail within the text. The infectious potential of these specimens depends mainly on the time of specimen collection and the presence of live replicating viral particles.

General & Internal Medicine

Life Sciences & Biomedicine

Medicine, General & Internal

Science & Technology

Details

Title: Subtitle: Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence Summary
Creators: Sajjad Shirazi - University of Illinois Chicago
Clark M. Stanford - University of Illinois Chicago
Lyndon F. Cooper - University of Illinois Chicago
Resource Type: Journal article
Publication Details: Journal of clinical medicine, Vol.10(6), pp.1-12
DOI: 10.3390/jcm10061158
PMID: 33802043
PMCID: PMC8000787
NLM abbreviation: J Clin Med
ISSN: 2077-0383
eISSN: 2077-0383
Publisher: Mdpi
Number of pages: 12
Language: English
Date published: 03/01/2021
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Dentistry Administration; Prosthodontics; Orthopedics and Rehabilitation; Craniofacial Anomalies Research Center
Record Identifier: 9984367748702771

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