Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria

Olukemi Adekanmbi; Olayinka Ilesanmi; Olusola Idowu; Arinola Esan; Yemi R Raji; Adeola Fowotade; Olubunmi Ogunlade; Adegboyega Akere; Oluwaseun Ololade; Kehinde Ojifinni; Olurotimi Akinola; Akintunde Orunmuyi; Uwom Eze; Victor Akinmoladun; Abiodun Adeoye; Akindele Adebiyi; E Oluwabunmi Olapade-Olaopa; Jesse A Otegbayo; Kayode Osungbade

doi:10.4314/ahs.v23i1.9

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Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria

Journal article

Open access

Peer reviewed

Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria

Olukemi Adekanmbi, Olayinka Ilesanmi, Olusola Idowu, Arinola Esan, Yemi R Raji, Adeola Fowotade, Olubunmi Ogunlade, Adegboyega Akere, Oluwaseun Ololade, Kehinde Ojifinni, …

African health sciences, Vol.23(1), pp.72-82

03/01/2023

DOI: 10.4314/ahs.v23i1.9

PMCID: PMC10398429

PMID: 37545917

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Abstract

Data regarding the features and outcomes of hospitalized COVID-19 patients in Africa are increasingly available. To describe socio-demographic, clinical and laboratory characteristics and outcomes of COVID-19 patients. A cross-sectional study of 86 adult patients hospitalized with COVID-19 between March and November 2020. Characteristics were described in survivors and non-survivors. Mean age was 60.9±16.1 years, 53(61.6%) were male. Co-morbidities were found in 77(89.5%) patients. On severity, 6(7%) were mild, 23(26.7%) moderate, 51(59.3%) severe and 6(7%) critical. Oxygen saturation and respiratory rate were 71±22% and 38±11/minute in non-survivors and 90±7% and 31±7/minute in survivors respectively (p<0.001, p<0.001)). Overall mortality was 47.7% with no death among patients with mild disease and deaths in all patients with critical disease. Duration of hospitalization was 2.0(1.0-4.5) days in those who died and 12(7.0-15.0) days in those who survived (p<0.001). Of the 42 patients that received dexamethasone, 11(26.2%) died, while 31(73.8%) survived (p=<0.001). Most of the patients had co-morbidities and there was high mortality in patients with severe and critical COVID-19. Mean oxygen saturation was low and respiratory rate high overall. Factors associated with mortality included: Significantly greater hypoxia and tachypnea, less dexamethasone use and shorter hospitalization.

Adult

Aged

COVID-19 - epidemiology

COVID-19 - therapy

Cross-Sectional Studies

Dexamethasone

Female

Hospitalization

Humans

Male

Middle Aged

Nigeria - epidemiology

Retrospective Studies

SARS-CoV-2

Tertiary Care Centers

Details

Title: Subtitle: Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria
Creators: Olukemi Adekanmbi - University of Ibadan
Olayinka Ilesanmi - University College Hospital, Ibadan
Olusola Idowu - University of Ibadan
Arinola Esan - University College Hospital, Ibadan
Yemi R Raji - University of Ibadan
Adeola Fowotade - University of Ibadan
Olubunmi Ogunlade - University College Hospital, Ibadan
Adegboyega Akere - University of Ibadan
Oluwaseun Ololade - University College Hospital, Ibadan
Kehinde Ojifinni - University College Hospital, Ibadan
Olurotimi Akinola - University College Hospital, Ibadan
Akintunde Orunmuyi - University of Ibadan
Uwom Eze - University College Hospital, Ibadan
Victor Akinmoladun - University of Ibadan
Abiodun Adeoye - University College Hospital, Ibadan
Akindele Adebiyi - University College Hospital, Ibadan
E Oluwabunmi Olapade-Olaopa - University College Hospital, Ibadan
Jesse A Otegbayo - University of Ibadan
Kayode Osungbade - University of Ibadan
Resource Type: Journal article
Publication Details: African health sciences, Vol.23(1), pp.72-82
DOI: 10.4314/ahs.v23i1.9
PMID: 37545917
PMCID: PMC10398429
NLM abbreviation: Afr Health Sci
ISSN: 1680-6905
eISSN: 1729-0503
Language: English
Date published: 03/01/2023
Academic Unit: Anesthesia
Record Identifier: 9984787257502771

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