Characterization of Whole Body Pain in Urological Chronic Pelvic Pain Syndrome at Baseline: A MAPP Research Network Study

H. Henry Lai; Thomas Jemielita; Siobhan Sutcliffe; Catherine S Bradley; Bruce Naliboff; David A Williams; Robert W Gereau; Karl Kreder; J. Quentin Clemens; Larissa V Rodriguez; John N Krieger; John T Farrar; Nancy Robinson; J. Richard Landis; MAPP Research Network

doi:10.1016/j.juro.2017.03.132

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Characterization of Whole Body Pain in Urological Chronic Pelvic Pain Syndrome at Baseline: A MAPP Research Network Study

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Characterization of Whole Body Pain in Urological Chronic Pelvic Pain Syndrome at Baseline: A MAPP Research Network Study

H. Henry Lai, Thomas Jemielita, Siobhan Sutcliffe, Catherine S Bradley, Bruce Naliboff, David A Williams, Robert W Gereau, Karl Kreder, J. Quentin Clemens, Larissa V Rodriguez, …

The Journal of Urology, Vol.198(3), pp.622-631

09/2017

DOI: 10.1016/j.juro.2017.03.132

PMID: 28373134

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Abstract

We characterized the location and spatial distribution of whole body pain in patients with urological chronic pelvic pain syndrome using a body map. We also compared the severity of urinary symptoms, pelvic pain, nonpelvic pain and psychosocial health among patients with different pain patterns. A total of 233 women and 191 men with urological chronic pelvic pain syndrome enrolled in a multicenter, 1-year observational study completed a battery of baseline measures, including a body map describing the location of pain during the last week. Participants were categorized with pelvic pain if they reported pain in the abdomen and pelvis only. Participants who reported pain beyond the pelvis were further divided into 2 subgroups based on the number of broader body regions affected by pain, including an intermediate group with 1 or 2 additional regions outside the pelvis and a widespread pain group with 3 to 7 additional regions. Of the 424 enrolled patients 25% reported pelvic pain only and 75% reported pain beyond the pelvis, of whom 38% reported widespread pain. Participants with a greater number of pain locations had greater nonpelvic pain severity (p <0.0001), sleep disturbance (p = 0.035), depression (p = 0.005), anxiety (p = 0.011), psychological stress (p = 0.005) and negative affect scores (p = 0.0004), and worse quality of life (p ≤0.021). No difference in pelvic pain and urinary symptom severity was observed according to increasing pain distribution. Three-quarters of the men and women with urological chronic pelvic pain syndrome reported pain outside the pelvis. Widespread pain was associated with greater severity of nonpelvic pain symptoms, poorer psychosocial health and worse quality of life but not with worse pelvic pain or urinary symptoms.

prostate

cystitis

pelvic pain

prostatitis

urinary bladder

interstitial

Details

Title: Subtitle: Characterization of Whole Body Pain in Urological Chronic Pelvic Pain Syndrome at Baseline: A MAPP Research Network Study
Creators: H. Henry Lai - Division of Urologic Surgery, Washington University School of Medicine, St. Louis, Missouri
Thomas Jemielita - Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
Siobhan Sutcliffe - Division of Public Health Sciences, Washington University School of Medicine, St. Louis, Missouri
Catherine S Bradley - Department of Obstetrics and Gynecology, University of Iowa School of Medicine, Iowa City, Iowa
Bruce Naliboff - Departments of Medicine and Psychiatry and Biobehavioral Sciences, University of California School of Medicine, Los Angeles, California
David A Williams
Robert W Gereau - Department of Surgery and Department of Anesthesiology and Washington University Pain Center, Washington University School of Medicine, St. Louis, Missouri
Karl Kreder - Department of Urology, University of Iowa School of Medicine, Iowa City, Iowa
J. Quentin Clemens - Department of Urology, University of Michigan School of Medicine, Ann Arbor, Michigan
Larissa V Rodriguez - Departments of Urology and Obstetrics and Gynecology, University of Southern California, Los Angeles, California
John N Krieger - Department of Urology, University of Washington School of Medicine, Seattle, Washington
John T Farrar - Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
Nancy Robinson - Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
J. Richard Landis - Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
MAPP Research Network
Resource Type: Journal article
Publication Details: The Journal of Urology, Vol.198(3), pp.622-631
DOI: 10.1016/j.juro.2017.03.132
PMID: 28373134
NLM abbreviation: J Urol
ISSN: 0022-5347
eISSN: 1527-3792
Publisher: Elsevier Inc
Language: English
Date published: 09/2017
Academic Unit: Epidemiology; Obstetrics and Gynecology; Urology
Record Identifier: 9983930420402771

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