Characterization of acute experimental left ventricular thrombi with quantitative backscatter imaging

Byron F Vandenberg; Robert A Kieso; Karen Fox-Eastham; Richard E Kerber; Hewlett E Melton; Steve M Collins; David J Skorton

doi:10.1161/01.CIR.81.3.1017

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Characterization of acute experimental left ventricular thrombi with quantitative backscatter imaging

Byron F Vandenberg, Robert A Kieso, Karen Fox-Eastham, Richard E Kerber, Hewlett E Melton, Steve M Collins and David J Skorton

Circulation (New York, N.Y.), Vol.81(3), pp.1017-1023

1990

DOI: 10.1161/01.CIR.81.3.1017

PMID: 2306814

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Abstract

Two-dimensional echocardiography is an excellent technique for detecting left ventricular thrombi, however, acute clot is sometimes difficult to differentiate from adjacent myocardium and intracavitary signals. We hypothesized that quantitative assessment of the acoustic properties of acute left ventricular thrombi using a quantitative backscatter imaging system would permit the differentiation of thrombus from adjacent myocardium and intracavitary echoes. Acute, experimental left ventricular thrombi in seven dogs were evaluated with a quantitative backscatter imaging system that allowed the measurement of relative integrated backscatter and cyclic (i.e., diastolic minus systolic) variation in integrated backscatter. Coronary ligation abolished the cyclic variation in relative backscatter that occurred in normal myocardium. The end-diastolic relative backscatter in the thrombus (16.9 +/- 1.3 dB) was significantly higher than in apical myocardium (13.2 +/- 0.6 dB, p less than 0.05). There was no significant difference in the cyclic variation in relative backscatter among thrombus, ischemic myocardium, or intracavitary blood. Thus, the quantitative assessment of the acoustic properties of left ventricular thrombi can be useful in their detection and in the differentiation from myocardium and intracavitary signals.

Cardiology. Vascular system

Biological and medical sciences

Medical sciences

Details

Title: Subtitle: Characterization of acute experimental left ventricular thrombi with quantitative backscatter imaging
Creators: Byron F Vandenberg - Univ. Iowa, cardiovascular cent., Iowa City IA 52242, United States
Robert A Kieso - Univ. Iowa, cardiovascular cent., Iowa City IA 52242, United States
Karen Fox-Eastham - Univ. Iowa, cardiovascular cent., Iowa City IA 52242, United States
Richard E Kerber - Univ. Iowa, cardiovascular cent., Iowa City IA 52242, United States
Hewlett E Melton - Univ. Iowa, cardiovascular cent., Iowa City IA 52242, United States
Steve M Collins - Univ. Iowa, cardiovascular cent., Iowa City IA 52242, United States
David J Skorton - Univ. Iowa, cardiovascular cent., Iowa City IA 52242, United States
Resource Type: Journal article
Publication Details: Circulation (New York, N.Y.), Vol.81(3), pp.1017-1023
DOI: 10.1161/01.CIR.81.3.1017
PMID: 2306814
NLM abbreviation: Circulation
ISSN: 0009-7322
eISSN: 1524-4539
Publisher: Lippincott Williams & Wilkins
Language: English
Date published: 1990
Academic Unit: Radiology; Electrical and Computer Engineering; Cardiovascular Medicine; Internal Medicine
Record Identifier: 9984094776902771

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