Journal article
Characterization of the light-induced currents in Hermissenda
Neurocomputing (Amsterdam), Vol.32(1-4), pp.45-49
06/01/2000
DOI: 10.1016/S0925-2312(00)00142-9
Abstract
Classical conditioning of the seaslug,
Hermissenda crassicornis, with light and turbulence produces changes in the membrane properties of type B photoreceptors. The light response consists of a generator potential, which persists for the duration of the light flash, followed by a smaller, long lasting depolarization (LLD). Voltage clamp data suggests that two currents generate the light response: a transient sodium current, previously modeled as an IP
3-gated sodium current, and a smaller, prolonged current that is sensitive to calcium. A model of the calcium-sensitive light-induced current is developed and included in a model with previously characterized light-induced and voltage-dependent currents. Voltage clamp simulations using this five channel model show that the calcium sensitive component consists of both a sodium current and a potassium current, and that both of them are required for the LLD.
Details
- Title: Subtitle
- Characterization of the light-induced currents in Hermissenda
- Creators
- K.T Blackwell - George Mason University
- Resource Type
- Journal article
- Publication Details
- Neurocomputing (Amsterdam), Vol.32(1-4), pp.45-49
- DOI
- 10.1016/S0925-2312(00)00142-9
- ISSN
- 0925-2312
- eISSN
- 1872-8286
- Publisher
- Elsevier B.V
- Language
- English
- Date published
- 06/01/2000
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Iowa Neuroscience Institute
- Record Identifier
- 9984446411002771
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