Characterizing alcohol dependence: transitions during young and middle adulthood

Kristina M Jackson; Susan E O'Neill; Kenneth J Sher

doi:10.1037/1064-1297.14.2.228

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Characterizing alcohol dependence: transitions during young and middle adulthood

Journal article

Peer reviewed

Characterizing alcohol dependence: transitions during young and middle adulthood

Kristina M Jackson, Susan E O'Neill and Kenneth J Sher

Experimental and clinical psychopharmacology, Vol.14(2), pp.228-244

05/2006

DOI: 10.1037/1064-1297.14.2.228

PMCID: PMC2898714

PMID: 16756427

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https://www.ncbi.nlm.nih.gov/pmc/articles/2898714View

Open Access

Abstract

Community and high-risk sample studies suggest that alcohol dependence is relatively stable and chronic. By contrast, epidemiological studies demonstrate a strong age-graded decline whereby alcohol dependence tends to peak in early adulthood and declines thereafter. The authors identified the latent trajectory structure of past-year alcohol dependence to investigate (a) whether the syndrome is characterized by symptom profiles and (b) the extent to which the syndrome is stable and persistent. Data from current drinkers (N = 4,003) in the National Longitudinal Survey of Youth were analyzed across two waves: 1989 (ages 24-32 years) and 1994 (ages 29-37 years). Three classes of alcohol dependence were observed; symptom endorsement probabilities increased across successively severe classes. Latent transition analyses showed high rates of stability, supporting alcohol dependence as a relatively chronic condition. Although there was evidence of progression to more severe dependence, there was greater syndrome remission. Trajectory classes and transition probabilities were generalizable across race and sex and, to a lesser extent, age cohort and family history of alcoholism.

Adolescent

Adult

Age Factors

Alcohol-Related Disorders - epidemiology

Alcohol-Related Disorders - psychology

Cross-Sectional Studies

Female

Humans

Male

Probability

Sex Characteristics

Details

Title: Subtitle: Characterizing alcohol dependence: transitions during young and middle adulthood
Creators: Kristina M Jackson - University of Missouri
Susan E O'Neill - University of Missouri
Kenneth J Sher - University of Missouri
Resource Type: Journal article
Publication Details: Experimental and clinical psychopharmacology, Vol.14(2), pp.228-244
DOI: 10.1037/1064-1297.14.2.228
PMID: 16756427
PMCID: PMC2898714
NLM abbreviation: Exp Clin Psychopharmacol
ISSN: 1064-1297
eISSN: 1936-2293
Grant note: R01 AA013987 / NIAAA NIH HHS R37 AA13987 / NIAAA NIH HHS K01 AA013938-02 / NIAAA NIH HHS R01 AA07231 / NIAAA NIH HHS P50 AA011998 / NIAAA NIH HHS R01 AA007231 / NIAAA NIH HHS K01 AA013938 / NIAAA NIH HHS K01 AA13938 / NIAAA NIH HHS P50 AA11998 / NIAAA NIH HHS
Language: English
Date published: 05/2006
Academic Unit: Psychological and Brain Sciences
Record Identifier: 9984719845102771

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